Iron-catalyzed C-H/N-H activation by triazole guidance: versatile alkyne annulation

被引:50
作者
Cera, G. [1 ]
Haven, T. [1 ]
Ackermann, L. [1 ]
机构
[1] Georg August Univ, Inst Organ & Biomol Chem, Tammannstr 2, D-37077 Gottingen, Germany
基金
欧洲研究理事会;
关键词
BOND ACTIVATION; DIRECTING GROUP; OXIDATIVE CYCLOADDITION; DIRECT ARYLATIONS; ACID-DERIVATIVES; AROMATIC AMIDES; FUNCTIONALIZATION; BENZAMIDES; ISOQUINOLONE; ALKENES;
D O I
10.1039/c7cc03376a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Iron-catalyzed C-H/N-H functionalizations were achieved by the aid of modular triazole amides. The alkyne annulation allowed for the expedient synthesis of valuable isoquinolone scaffolds with high levels of chemo-, site- and regio-selectivities.
引用
收藏
页码:6460 / 6463
页数:4
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