Reduced graphene oxide/titanium dioxide hybrid nanofiller-reinforced electrospun silk fibroin scaffolds for tissue engineering

被引：27
作者：
Zhang, Chao [1 ]
Wang, Xinru [1 ]
Liu, Aihui [1 ]
Pan, Changjiang [1 ]
Ding, Hongyan [2 ]
Ye, Wei [1 ]
机构：
[1] Huaiyin Inst Technol, Fac Mech & Mat Engn, Jiangsu Prov Engn Res Ctr Biomed Mat & Adv Med De, Huaian 223003, Peoples R China
[2] Suqian Coll, Suqian 223800, Peoples R China
来源：
MATERIALS LETTERS | 2021年 / 291卷
基金：
中国国家自然科学基金;
关键词：
Biomaterials; Silk fibroin; Graphene oxide; Titanium dioxide; Composite materials; Electrospinning; MECHANICAL-PROPERTIES; OXIDE; FIBERS;
D O I：
10.1016/j.matlet.2021.129563
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Reduced graphene oxide/titanium dioxide (RGO@TiO2) hybrid nanoparticle was synthesized and used as a filler to study the synergistic effects on electrospun regenerated silk fibroin (RSF) mats. The incorporation of the hybrid filler increased the average diameter of RSF fibers, but decreased the content of beta-sheet conformation. The breaking strength of RSF/RGO@TiO2 composite mat increased by 220%. Moreover, the composite mat supported the growth and expansion of cells and had a good antibacterial property. This study may provide a new development perspective of multifunctional nanocomposite based on RGO@TiO2 hybrid filler. (C) 2021 Elsevier B.V. All rights reserved.
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页数：4
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