Extracorporeal membrane oxygenation support in children with severe coronavirus disease-2019: A case series

被引：0

作者：

Cavalcante, Candice Torres de Melo Bezerra ^{[1
]}

Teles, Andrea Consuelo de Oliveira ^{[1
]}

Maia, Isabel Cristina Leite ^{[1
]}

Pinto, Valdester Cavalcante ^{[1
]}

Banderira, Jeanne Araujo ^{[1
,2
]}

Cruz, Emanoel Pimentel ^{[1
]}

Onofre, Raimunda Selma Antero Sousa ^{[1
]}

Pombo, Fabricio Barreira ^{[1
]}

Cavalcante, Marcelo Borges ^{[2
,3
]}

Branco, Klebia Magalhaes Pereira Castello ^{[1
]}

机构：

[1] Hosp Dr Carlos Alberto Studart Gomes, Ave Washington Soares,1321-Edson Queiroz, BR-60811905 Fortaleza, Brazil

[2] Univ Fortaleza, Med Course, UNIFOR, Fortaleza, CE, Brazil

[3] Univ Fortaleza, Postgrad Program Med Sci, UNIFOR, Fortaleza, CE, Brazil

来源：

LANCET REGIONAL HEALTH-AMERICAS | 2022年 / 11卷

关键词：

Child; COVID-19; Respiratory distress syndrome; Extracorporeal membrane oxygenation;

D O I：

暂无

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

Background The coronavirus disease-2019 (COVID-19) pandemic has predominantly affected the adult population, but with a significantly lower prevalence in children. Most pediatric patients with COVID-19 have mild course; how-ever, a small number progressed to acute respiratory distress syndrome, hypoxemia, despite optimized conventional therapies. Thus, this study aimed to report a series of six cases of children with severe acute respiratory syndrome coronavirus 2 infection who were supported by extracorporeal membrane oxygenation (ECMO) due to refractory hypoxemic respiratory failure.Methods This observational, retrospective, and descriptive study reported a series of cases. Data were retrospectively collected from the medical records of patients who were admitted to the Pediatric Cardiologic Intensive Care of Hos-pital Dr. Carlos Alberto Studart Gomes and Hospital Regional da Unimed, between March 1, 2020, and June 30, 2021. Sociodemographic, clinical, and laboratory data were analyzed.Findings The median age was 1.8 years (range: 0.4-14.5 years), 66.7% were males, and weight varied from 13 to 110 kg. The mean time between the onset of symptoms and cannulation, ECMO duration, and ventilation time were 15 days (range: 6-24 days)], 11 days (range: 6-19 days), and 20.5 days (range: 14-33 days), respectively. Five (83.3%) children were successfully decannulated and four survived with hospital discharge. One child died on ECMO sup-port due to multiple organ dysfunction syndromes after 13 days and another one died 3 days after decannulation due to extensive hemorrhagic stroke. Our case series revealed a 33.3% in-hospital mortality rate. ECMO appears as a via-ble intervention in selected patients who failed conventional therapies in the pediatric population.Funding This observational study received no funding.Copyright (c) 2022 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)

引用

页数：10