New rubrolides from the ascidian Synoicum blochmanni

被引：107

作者：

Ortega, MJ ^{[1
]}

Zubía, E ^{[1
]}

Ocaña, JM ^{[1
]}

Naranjo, S ^{[1
]}

Salvá, J ^{[1
]}

机构：

[1] Fac Ciencias Mar, Dept Quim Organ, Cadiz 11510, Spain

来源：

TETRAHEDRON | 2000年 / 56卷 / 24期

关键词：

marine metabolites; biologically active compounds;

D O I：

10.1016/S0040-4020(00)00328-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The ascidian Synoicum blochmanni has been investigated as a part of our ongoing project directed towards the search for pharmacologically active marine natural products. The chemical study of S. blochmanni has afforded, in addition to four known compounds, six new members of the rubrolide family. Their structures were defined by spectroscopic methods with special emphasis in 1D and 2D NMR and MS. The cytotoxicities exhibited by the compounds of S, blochmanni against several cancer cell lines are presented. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：3963 / 3967

页数：5

共 6 条

[1] Facile access to 4-aryl-2(5H)-furanones by Suzuki cross coupling:: Efficient synthesis of rubrolides C and E [J].