Physical Activity, Aging, and Physiological Function

被引:140
作者
Harridge, Stephen D. R. [1 ]
Lazarus, Norman R. [1 ]
机构
[1] Kings Coll London, Ctr Human & Aerosp Physiol Sci, Fac Life Sci & Med, London, England
关键词
MAXIMAL HEART-RATE; SKELETAL-MUSCLE; BODY-COMPOSITION; CARDIOVASCULAR-DISEASE; CONTRACTILE PROPERTIES; EXERCISE PERFORMANCE; ENDURANCE EXERCISE; AEROBIC CAPACITY; CARDIAC-OUTPUT; BRAIN HEALTH;
D O I
10.1152/physiol.00029.2016
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Human evolution suggests that the default position for health is to be physically active. Inactivity, by contrast, has serious negative effects on health across the lifespan. Therefore, only in physically active people can the inherent aging process proceed unaffected by disuse complications. In such individuals, although the relationship between age and physiological function remains complex, function is generally superior with health, well being, and the aging process optimized.
引用
收藏
页码:152 / 161
页数:10
相关论文
共 95 条
[1]   Human skeletal muscle fibroblasts, but not myogenic cells, readily undergo adipogenic differentiation [J].
Agley, Chibeza C. ;
Rowlerson, Anthea M. ;
Velloso, Cristiana P. ;
Lazarus, Norman R. ;
Harridge, Stephen D. R. .
JOURNAL OF CELL SCIENCE, 2013, 126 (24) :5610-5625
[2]   Effect of aging and physical activity on left ventricular compliance [J].
Arbab-Zadeh, A ;
Dijk, E ;
Prasad, A ;
Fu, Q ;
Torres, P ;
Zhang, R ;
Thomas, JD ;
Palmer, D ;
Levine, BD .
CIRCULATION, 2004, 110 (13) :1799-1805
[3]   Aging Performance for Masters Records in Athletics, Swimming, Rowing, Cycling, Triathlon, and Weightlifting [J].
Baker, A. Barry ;
Tang, Yong Q. .
EXPERIMENTAL AGING RESEARCH, 2010, 36 (04) :453-477
[4]   Percentage decline in masters superathlete track and field performance with aging [J].
Baker, AB ;
Tang, YQ ;
Turner, MJ .
EXPERIMENTAL AGING RESEARCH, 2003, 29 (01) :47-65
[5]   Limiting factors for maximum oxygen uptake and determinants of endurance performance [J].
Bassett, DR ;
Howley, ET .
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 2000, 32 (01) :70-84
[6]   Impact of Lifelong Exercise "Dose" on Left Ventricular Compliance and Distensibility [J].
Bhella, Paul S. ;
Hastings, Jeffrey L. ;
Fujimoto, Naoki ;
Shibata, Shigeki ;
Carrick-Ranson, Graeme ;
Palmer, M. Dean ;
Boyd, Kara N. ;
Adams-Huet, Beverley ;
Levine, Benjamin D. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2014, 64 (12) :1257-1266
[7]   Influences of cardiorespiratory fitness and other precursors on cardiovascular disease and all-cause mortality in men and women [J].
Blair, SN ;
Kampert, JB ;
Kohl, HW ;
Barlow, CE ;
Macera, CA ;
Paffenbarger, RS ;
Gibbons, LW .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1996, 276 (03) :205-210
[8]   Lack of Exercise Is a Major Cause of Chronic Diseases [J].
Booth, Frank W. ;
Roberts, Christian K. ;
Laye, Matthew J. .
COMPREHENSIVE PHYSIOLOGY, 2012, 2 (02) :1143-1211
[9]   Exercise and gene expression: physiological regulation of the human genome through physical activity [J].
Booth, FW ;
Chakravarthy, MV ;
Spangenburg, EE .
JOURNAL OF PHYSIOLOGY-LONDON, 2002, 543 (02) :399-411
[10]   Less Sitting, More Physical Activity, or Higher Fitness? [J].
Bouchard, Claude ;
Blair, Steven N. ;
Katzmarzyk, Peter T. .
MAYO CLINIC PROCEEDINGS, 2015, 90 (11) :1533-1540