From personalized to precision cancer medicine

被引：2
作者：
Baltagiannis, Evangelos G. [1 ,2 ]
Kyrochristos, Ioannis D. [1 ,2 ]
Ziogas, Demosthenes E. [1 ,3 ]
Goussia, Anna [4 ]
Mitsis, Michail [2 ,5 ]
Roukos, Dimitrios H. [1 ,2 ,6 ]
机构：
[1] Ioannina Univ, Ctr Biosyst & Genome Network Med, Ioannina, Greece
[2] Univ Hosp Ioannina, Dept Surg, Ioannina, Greece
[3] G Hatzikosta Gen Hosp, Dept Surg, Ioannina, Greece
[4] Univ Hosp Ioannina, Dept Pathol, Ioannina, Greece
[5] Ioannina Univ, Canc Biobank Ctr, Ioannina, Greece
[6] Acad Athens BRFAA, Biomed Res Fdn, Dept Syst Biol, Athens, Greece
来源：
PERSONALIZED MEDICINE | 2020年 / 17卷 / 04期
关键词：
cancer precision medicine; combinatorial therapies; genome; genome engineering; intratumor heterogeneity; next-generation sequencing; predictive biomarkers; regulatory networks; single-cell sequencing; transcriptome; DRUG DEVELOPMENT; GENOMIC CLONES; CRISPR-CAS; DISCOVERY; THERAPY;
D O I：
10.2217/pme-2020-0056
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：245 / 250
页数：6
相关论文
共 35 条
  • [1] [Anonymous], 2020, NATURE, V578, P7, DOI 10.1038/d41586-020-00308-w
  • [2] [Anonymous], 1972, J Natl Cancer Inst, V48, P577
  • [3] A clonal expression biomarker associates with lung cancer mortality
    Biswas, Dhruva
    Birkbak, Nicolai J.
    Rosenthal, Rachel
    Hiley, Crispin T.
    Lim, Emilia L.
    Papp, Krisztian
    Boeing, Stefan
    Krzystanek, Marcin
    Djureinovic, Dijana
    La Fleur, Linnea
    Greco, Maria
    Doeme, Balazs
    Fillinger, Janos
    Brunnstrom, Hans
    Wu, Yin
    Moore, David A.
    Skrzypski, Marcin
    Abbosh, Christopher
    Litchfield, Kevin
    Al Bakir, Maise
    Watkins, Thomas B. K.
    Veeriah, Selvaraju
    Wilson, Gareth A.
    Jamal-Hanjani, Mariam
    Moldvay, Judit
    Botling, Johan
    Chinnaiyan, Arul M.
    Micke, Patrick
    Hackshaw, Allan
    Bartek, Jiri
    Csabai, Istvan
    Szallasi, Zoltan
    Herrero, Javier
    McGranahan, Nicholas
    Swanton, Charles
    [J]. NATURE MEDICINE, 2019, 25 (10) : 1540 - +
  • [4] Genomic basis for RNA alterations in cancer
    Calabrese, Claudia
    Davidson, Natalie R.
    Demircioglu, Deniz
    Fonseca, Nuno A.
    He, Yao
    Kahles, Andre
    Kjong-Van Lehmann
    Liu, Fenglin
    Shiraishi, Yuichi
    Soulette, Cameron M.
    Urban, Lara
    Greger, Liliana
    Li, Siliang
    Liu, Dongbing
    Perry, Marc D.
    Xiang, Qian
    Zhang, Fan
    Zhang, Junjun
    Bailey, Peter
    Erkek, Serap
    Hoadley, Katherine A.
    Hou, Yong
    Huska, Matthew R.
    Kilpinen, Helena
    Korbel, Jan O.
    Marin, Maximillian G.
    Markowski, Julia
    Nandi, Tannistha
    Pan-Hammarstrom, Qiang
    Pedamallu, Chandra Sekhar
    Siebert, Reiner
    Stark, Stefan G.
    Su, Hong
    Tan, Patrick
    Waszak, Sebastian M.
    Yung, Christina
    Zhu, Shida
    Awadalla, Philip
    Creighton, Chad J.
    Meyerson, Matthew
    Ouellette, B. F. Francis
    Wu, Kui
    Yang, Huanming
    Brazma, Alvis
    Brooks, Angela N.
    Goke, Jonathan
    Raetsch, Gunnar
    Schwarz, Roland F.
    Stegle, Oliver
    Zhang, Zemin
    [J]. NATURE, 2020, 578 (7793) : 129 - +
  • [5] Cieslik M, 2020, NATURE, V578, P39, DOI 10.1038/d41586-020-00213-2
  • [6] RNA editing with CRISPR-Cas13
    Cox, David B. T.
    Gootenberg, Jonathan S.
    Abudayyeh, Omar O.
    Franklin, Brian
    Kellner, Max J.
    Joung, Julia
    Zhang, Feng
    [J]. SCIENCE, 2017, 358 (6366) : 1019 - 1027
  • [7] Genome-wide cell-free DNA fragmentation in patients with cancer
    Cristiano, Stephen
    Leal, Alessandro
    Phallen, Jillian
    Fiksel, Jacob
    Adleff, Vilmos
    Bruhm, Daniel C.
    Jensen, Sarah Ostrup
    Medina, Jamie E.
    Hruban, Carolyn
    White, James R.
    Palsgrove, Doreen N.
    Niknafs, Noushin
    Anagnostou, Valsamo
    Forde, Patrick
    Naidoo, Jarushka
    Marrone, Kristen
    Brahmer, Julie
    Woodward, Brian D.
    Husain, Hatim
    van Rooijen, Karlijn L.
    Orntoft, Mai-Britt Worm
    Madsen, Anders Husted
    van de Velde, Cornelis J. H.
    Verheij, Marcel
    Cats, Annemieke
    Punt, Cornelis J. A.
    Vink, Geraldine R.
    van Grieken, Nicole C. T.
    Koopman, Miriam
    Fijneman, Remond J. A.
    Johansen, Julia S.
    Nielsen, Hans Jorgen
    Meijer, Gerrit A.
    Andersen, Claus Lindbjerg
    Scharpf, Robert B.
    Velculescu, Victor E.
    [J]. NATURE, 2019, 570 (7761) : 385 - +
  • [8] Drug development in the era of precision medicine
    Dugger, Sarah A.
    Platt, Adam
    Goldstein, David B.
    [J]. NATURE REVIEWS DRUG DISCOVERY, 2018, 17 (03) : 183 - 196
  • [9] Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution
    Eirew, Peter
    Steif, Adi
    Khattra, Jaswinder
    Ha, Gavin
    Yap, Damian
    Farahani, Hossein
    Gelmon, Karen
    Chia, Stephen
    Mar, Colin
    Wan, Adrian
    Laks, Emma
    Biele, Justina
    Shumansky, Karey
    Rosner, Jamie
    McPherson, Andrew
    Nielsen, Cydney
    Roth, Andrew J. L.
    Lefebvre, Calvin
    Bashashati, Ali
    de Souza, Camila
    Siu, Celia
    Aniba, Radhouane
    Brimhall, Jazmine
    Oloumi, Arusha
    Osako, Tomo
    Bruna, Alejandra
    Sandoval, Jose L.
    Algara, Teresa
    Greenwood, Wendy
    Leung, Kaston
    Cheng, Hongwei
    Xue, Hui
    Wang, Yuzhuo
    Lin, Dong
    Mungall, Andrew J.
    Moore, Richard
    Zhao, Yongjun
    Lorette, Julie
    Long Nguyen
    Huntsman, David
    Eaves, Connie J.
    Hansen, Carl
    Marra, Marco A.
    Caldas, Carlos
    Shah, Sohrab P.
    Aparicio, Samuel
    [J]. NATURE, 2015, 518 (7539) : 422 - 426
  • [10] Optical Pooled Screens in Human Cells
    Feldman, David
    Singh, Avtar
    Schmid-Burgk, Jonathan L.
    Carlson, Rebecca J.
    Mezger, Anja
    Garrity, Anthony J.
    Zhang, Feng
    Blainey, Paul C.
    [J]. CELL, 2019, 179 (03) : 787 - +
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