Modern information technologies such as big data and cloud computing are increasingly important and widely applied in engineering and management. In terms of cold chain logistics, data mining also exerts positive effects on it. Specifically, accurate prediction of cold chain logistics demand is conducive to optimizing management processes as well as improving management efficiency, which is the main purpose of this research. In this paper, we analyze the existing problems related to cold chain logistics in the context of Chinese market, especially the aspect of demand prediction. Then, we conduct the mathematical calculation based on the neural network algorithm and grey prediction. Two forecasting models are constructed with the data from 2013 to 2019 by R program 4.0.2, aiming to explore the cold chain logistics demand. According to the results estimated by the two models, we find that both of models show high accuracy. In particular, the prediction of neural network algorithm model is closer to the actual value with smaller errors. Therefore, it is better to consider the neural network algorithm as the first choice when constructing the mathematical forecasting model to predict the demand of cold chain logistic, which provides a more accurate reference for the strategic deployment of logistics management such as optimizing automation and innovation in cold chain processes to adapt to the trend.
