Hypoglycemic properties of aqueous bark extract of Ceiba pentandra in streptozotocin-induced diabetic rats

被引：33

作者：

Ladeji, O ^{[1
]}

Omekarah, I ^{[1
]}

Solomon, M ^{[1
]}

机构：

[1] Univ Jos, Fac Med Sci, Dept Biochem, Jos, Nigeria

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2003年 / 84卷 / 2-3期

关键词：

Ceiba pentandra; Bombacaceae; streptozotocin-induced diabetes; hypoglycaemic effect;

D O I：

10.1016/S0378-8741(02)00321-5

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The claim by Nigerian traditional herbal medicine practitioners that the silk cotton tree, Ceiba pentandra L. Gaertn (Bombacaceae) barks extract has antidiabetic properties was investigated. Diabetes mellitus was induced with streptozotocin and graded doses of the aqueous bark extract were then administered ad libitum in drinking water to the experimentally diabetic rats for 28 days. Administration of the aqueous bark extract caused a statistically significant reduction in plasma glucose level in streptozotocin induced diabetic rats. The extract appeared non-toxic as evidenced by normal serum levels of AST, ALT, ALP and bilirubin. The data appear to support the hypoglycemic effects of C pentandra. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：139 / 142

页数：4

共 13 条

[1]

BERGMEYER HU, 1974, METHOD ENZYMAT AN, P320

[2]

DALZIEL JM, 1955, USEFUL PLANTS W TROP, P297

[3]

Ford ES, 1999, AM J EPIDEMIOL, V149, P168, DOI 10.1093/oxfordjournals.aje.a009783

[4]

HIRT HM, 1998, NATURAL MED TROPICS, P53

[5]

KAFARU E, 1994, NATURES WORKSHOP PUB

[6] ESTIMATION OF PLASMA PHOSPHATASE BY DETERMINATION OF HYDROLYSED PHENOL WITH AMINO-ANTIPYRINE [J].

KIND, PRN ;

KING, EJ .

JOURNAL OF CLINICAL PATHOLOGY, 1954, 7 (04) :322-326

[7] EFFECTS OF LYTHRUM-SALICARIA IN NORMOGLYCEMIC RATS [J].

LAMELA, M ;

CADAVID, I ;

GATO, A ;

CALLEJA, JM .

JOURNAL OF ETHNOPHARMACOLOGY, 1985, 14 (01) :83-91

[8]

MAIDOURI A, COMMUNICATION

[9]

Malloy HT, 1937, J BIOL CHEM, V119, P481

[10]

Menant M., 1980, MED PLANTS E S E ASI

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