[1] Univ Tartu, Estonian Genome Ctr, Tartu, Estonia
[2] Univ Tartu, Inst Mol & Cell Biol, Dept Biotechnol, Tartu, Estonia
[3] Univ Tartu, Inst Math & Stat, Tartu, Estonia
[4] Univ Helsinki, Inst Mol Med Finland FIMM, Helsinki, Finland
[5] Broad Inst MIT & Harvard, Cambridge, MA USA
[6] Univ Liverpool, Dept Biostat, Liverpool, Merseyside, England