Components for integrated poly(dimethylsiloxane) microfluidic systems

被引：3
|
作者：
Ng, JMK [1 ]
Gitlin, I [1 ]
Stroock, AD [1 ]
Whitesides, GM [1 ]
机构：
[1] Harvard Univ, Dept Chem & Biol Chem, Cambridge, MA 02138 USA
来源：
ELECTROPHORESIS | 2002年 / 23卷 / 20期
关键词：
interfacing; microfluidics; poly(dimethylsiloxane); review;
D O I：
10.1002/1522-2683(200210)23:20<3461::AID-ELPS3461>3.0.CO;2-8
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
This review describes the design and fabrication of microfluidic systems in poly(dimethylsiloxane) (PDMS). PDMS is a soft polymer with attractive physical and chemical properties: elasticity, optical transparency, flexible surface chemistry, low permeability to water, and low electrical conductivity. Soft lithography makes fabrication of microfluidic systems in PDMS particularly easy. Integration of components, and interfacing of devices with the user, is also convenient and simpler in PDMS than in systems made in hard materials. Fabrication of both single and multilayer microfluidic systems is straightforward in PDMS. Several components are described in detail: a passive chaotic mixer, pneumatically actuated switches and valves, a magnetic filter, functional membranes, and optical components.
引用
收藏
页码：3461 / 3473
页数：13
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