Tinea Unguium: Diagnosis and Treatment in Practice

被引:29
作者
Asz-Sigall, Daniel [1 ]
Tosti, Antonella [2 ]
Arenas, Roberto [1 ]
机构
[1] Dr Manuel Gea Gonzalez Gen Hosp, Mycol Sect, Ave Calzada Tlalpan 4800,Secc 16, Mexico City 14080, DF, Mexico
[2] Univ Miami Hosp, Dept Dermatol & Cutaneous Surg, 1295 NW 14th St,South Bldg,Stes K,L&M, Miami, FL 33136 USA
关键词
Onychomycosis; Tinea unguium; Dermatophytes; Dermoscopy; Antifungal therapy; ONYCHOMYCOSIS; CLASSIFICATION; METAANALYSIS; THERAPIES; UPDATE;
D O I
10.1007/s11046-016-0078-4
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Onychomycosis is caused by dermatophytes, yeasts or non-dermatophyte molds; when caused by dermatophytes, it is called tinea unguium. The main etiological agents are Trichophyton rubrum and Trichophyton interdigitale. The most frequent types are distal and lateral subungual onychomycosis. Diagnosis usually requires mycological laboratory confirmation. Dermoscopy can be helpful and also biopsy is an excellent diagnostic method in uncommon cases or when mycological test is negative. Treatment must be chosen according to clinical type, number of affected nails and severity. The goal for antifungal therapy is the clearing of clinical signs or mycological cure.
引用
收藏
页码:95 / 100
页数:6
相关论文
共 22 条
[1]  
Arenas R, 2014, MICOLOGIA MED ILUSTR, P67
[2]  
Arenas R., 2015, UNHAS OQUE NOVO, P11
[3]   HLA-DR6 association confers increased resistance to T-rubrum onychomycosis in Mexican Mestizos [J].
Asz-Sigall, Daniel ;
Lopez-Garcia, Lirio ;
Elisa Vega-Memije, Maria ;
Maria Lacy-Niebla, Rosa ;
Garcia-Corona, Cristina ;
Ramirez-Renteria, Claudia ;
Granados, Julio ;
Villa, Antonio ;
Ameen, Mahreen ;
Arenas, Roberto .
INTERNATIONAL JOURNAL OF DERMATOLOGY, 2010, 49 (12) :1406-1409
[4]   Comparison of direct microscopy, culture and calcofluor white for the diagnosis of onychomycosis [J].
Bonifaz, Alexandro ;
Manuel Rios-Yuil, Jose ;
Arenas, Roberto ;
Araiza, Javier ;
Fernandez, Ramon ;
Mercadillo-Perez, Patricia ;
Maria Ponce-Olivera, Rosa .
REVISTA IBEROAMERICANA DE MICOLOGIA, 2013, 30 (02) :109-111
[5]   A New Classification System for Grading the Severity of Onychomycosis Onychomycosis Severity Index [J].
Carney, Caitlin ;
Tosti, Antonella ;
Daniel, Ralph ;
Scher, Richard ;
Rich, Phoebe ;
DeCoster, Jamie ;
Elewski, Boni .
ARCHIVES OF DERMATOLOGY, 2011, 147 (11) :1277-1282
[6]   Fungal melanonychia [J].
Finch, Justin ;
Arenas, Roberto ;
Baran, Robert .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2012, 66 (05) :830-841
[7]   Laser therapies for onychomycosis - critical evaluation of methods and effectiveness [J].
Francuzik, W. ;
Fritz, K. ;
Salavastru, C. .
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2016, 30 (06) :936-942
[8]  
García-Romero MT, 2012, ACTAS DERMO-SIFILOGR, V103, P59, DOI [10.1016/j.ad.2011.03.018, 10.1016/j.adengl.2011.03.017]
[9]   Treatment of refractory fingernail onychomycosis caused by nondermatophyte molds with methylaminolevulinate photodynamic therapy [J].
Gilaberte, Yolanda ;
Aspiroz, Carmen ;
Pilar Martes, M. ;
Alcalde, Victor ;
Espinel-Ingroff, Ana ;
Rezusta, Antonio .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2011, 65 (03) :669-671
[10]   Novel investigational therapies for onychomycosis: an update [J].
Gupta, Aditya K. ;
Studholme, Catherine .
EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2016, 25 (03) :297-305