A second Escherichia coli protein with CL synthase activity

被引：44

作者：

Guo, DG

Tropp, BE ^{[1
]}

机构：

[1] CUNY Queens Coll, PhD Program Biochem, Flushing, NY 11367 USA

[2] CUNY Queens Coll, Dept Chem & Biochem, Flushing, NY 11367 USA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS | 2000年 / 1483卷 / 02期

关键词：

cardiolipin; cardiolipin synthase; cls; f413; N-terminal deletion;

D O I：

10.1016/S1388-1981(99)00193-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Escherichia coli open reading frame f413, which has the potential to code for a polypeptide homologous to cardiolipin (CL) synthase. has been cloned. Its polypeptide product has a molecular mass of 48 kDa, is membrane-bound, and catalyzes CL formation but does not hydrolyze CL. A comparison of the sequences predicted for the polypeptides encoded by f413 and cls indicates that the N-terminal residues specified by cls may be unnecessary for CL synthase activity. Construction of a truncated cls gene and characterization of its polypeptide product have confirmed this conclusion. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：263 / 274

页数：12

共 33 条

[1] FURTHER-STUDIES ON CARDIOLIPIN PHOSPHODIESTERASE OF ESCHERICHIA-COLI
COLE, R
PROULX, P
[J]. CANADIAN JOURNAL OF BIOCHEMISTRY, 1977, 55 (12): : 1228 - 1232
[2] BIOSYNTHESIS OF CARDIOLIPIN IN MEMBRANES OF MICROCOCCUS-LYSODEIKTICUS
DESIERVO, AJ
SALTON, MRJ
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1971, 239 (02) : 280 - &
[3] New developments in phospholipase D
Exton, JH
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (25) : 15579 - 15582
[4] Activation of phospholipase D by phosphatidic acid -: Enhanced vesicle binding, phosphatidic acid Ca2+ interaction, or an allosteric effect?
Geng, D
Chura, J
Roberts, MF
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (20) : 12195 - 12202
[5] Catalytic mechanism of the phospholipase D superfamily proceeds via a covalent phosphohistidine intermediate
Gottlin, EB
Rudolph, AE
Zhao, Y
Matthews, HR
Dixon, JE
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (16) : 9202 - 9207
[6] Antibiotic-resistance cassettes for Bacillus subtilis
GueroutFleury, AM
Shazand, K
Frandsen, N
Stragier, P
[J]. GENE, 1995, 167 (1-2) : 335 - 336
[7] Cloning of the Bacillus firmus OF4 cls gene and characterization of its gene product
Guo, DG
Tropp, BE
[J]. BIOCHIMICA ET BIOPHYSICA ACTA-LIPIDS AND LIPID METABOLISM, 1998, 1389 (01): : 34 - 42
[8] Hanahan D., 1985, DNA CLONING, V1, P109
[9] GENETIC-REGULATION OF CARDIOLIPIN SYNTHASE IN ESCHERICHIA-COLI
HEBER, S
TROPP, BE
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1991, 1129 (01) : 1 - 12
[10] ACTIVE INCREASE IN CARDIOLIPIN SYNTHESIS IN THE STATIONARY GROWTH-PHASE AND ITS PHYSIOLOGICAL SIGNIFICANCE IN ESCHERICHIA-COLI
HIRAOKA, S
MATSUZAKI, H
SHIBUYA, I
[J]. FEBS LETTERS, 1993, 336 (02) : 221 - 224

← 1 2 3 4 →