Successful Treatment of Recalcitrant Primary Follicular Mucinosis with Indomethacin and Low-dose Intralesional Interferon Alpha

被引：10

作者：

Kim, Kyu Ri ^{[1
,3
]}

Lee, Ji Yeoun ^{[1
,3
]}

Kim, Mi Kyeong ^{[2
]}

Yoon, Tae Young ^{[1
,3
]}

机构：

[1] Chungbuk Natl Univ, Dept Dermatol, Sch Med, Cheongju 361763, South Korea

[2] Chungbuk Natl Univ, Dept Internal Med, Sch Med, Cheongju 361763, South Korea

[3] Chungbuk Natl Univ, Med Res Inst, Cheongju 361763, South Korea

来源：

ANNALS OF DERMATOLOGY | 2009年 / 21卷 / 03期

关键词：

Follicular mucinosis; Indomethacin; Interferon alpha; EOSINOPHILS;

D O I：

10.5021/ad.2009.21.3.285

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Follicular mucinosis (FM) is an epithelial reaction pattern that is characterized by the accumulation of mucinous material in the epithelial hair follicle sheath and the sebaceous glands. Although various pharmacological agents have been employed in an attempt to treat FM, effective therapeutic options have remained elusive. We experienced a recalcitrant form of primary FM that we successfully treated with indomethacin and low-dose intralesional interferon alpha (IFN alpha), respectively. To the best of our knowledge, the primary type of FM that responded to indomethacin and low-dose IFN a, respectively, in a single case has not been reported in the English medical literature. (Ann Dermatol 21(3) 285 similar to 287, 2009)

引用

页码：285 / 287

页数：3

共 15 条

[1] Eosinophils express a functional receptor for interferon alpha: Inhibitory role of interferon alpha on the release of mediators [J].