The Incidence of Postpartum Depression and Associated Factors Among Iranian Healthy Mothers: Findings of a Prospective Cohort Study

Background: The occurrence of some psychological and emotional crisis in pregnancy may lead to postpartum depression in mothers. Objectives: This prospective cohort study aimed to estimate the incidence of postpartum depression (PPD) and its associated factors among Iranian mothers. Methods: A total of 164 women in their third trimester of pregnancy were recruited through quota sampling from February to July 2018 in Kerman, Iran. Women suffering from depression were excluded. The remained healthy women (n = 164) were traced up to two months after the delivery. The incidence of PPD was calculated by dividing the number of new cases of depression within the postpartum period by the number of initial healthy mothers. The Edinburgh Postnatal Depression Scale was applied to detect PPD. The Cox regression model was used to assess PPD-related factors. Crude and adjusted hazard ratios, as well as their 95% confidence intervals (95% CI) were reported. P-values of < 0.05 were considered statistically significant. SPSS version 22 was used to analyze the data. Results: The incidence of PPD within the two months after delivery was 9.8% and was higher among mothers who had high-school diploma or lower (11.9% vs. 6.4%), had unplanned pregnancy (25% vs. 9.2%), underwent cesarean section (11.3% vs. 8.7%), or were multiparous (10.6% vs. 6.3%). The mean (SD) social support was lower among mothers with depression (69.1 +/- 13.1 vs. 77.4 +/- 16.6). There was significant association between type of delivery (adjusted hazard ratio [AHR] = 0.57, 95% confidence interval (95% CI) = 0.36; 0.97) and social support (AHR = 0.95, 95% CI = 0.93; 0.97) with PPD. Conclusions: In sum, the concerning incidence of PPD highlighted the need for establishment and strengthening of screening programs during the post-partum period. Families' knowledge about the significance of providing sufficient social support for mothers may have prevented this disorder and therefore, it was recommended that it should be incorporated into prenatal cares.