The prevalence and risks of major comorbidities among inpatients with pulmonary tuberculosis in China from a gender and age perspective: a large-scale multicenter observational study

被引：15

作者：

Kang, Wanli ^{[1
]}

Du, Jian ^{[1
]}

Yang, Song ^{[2
]}

Yu, Jiajia ^{[1
]}

Chen, Hongyan ^{[3
]}

Liu, Jianxiong ^{[4
]}

Ma, Jinshan ^{[5
]}

Li, Mingwu ^{[6
]}

Qin, Jingmin ^{[7
]}

Shu, Wei ^{[1
]}

Zong, Peilan ^{[8
]}

Zhang, Yi ^{[9
]}

Dong, Yongkang ^{[10
]}

Yang, Zhiyi ^{[11
]}

Mei, Zaoxian ^{[12
]}

Deng, Qunyi ^{[13
]}

Wang, Pu ^{[14
]}

Han, Wenge ^{[15
]}

Wu, Meiying ^{[16
]}

Chen, Ling ^{[17
]}

Zhao, Xinguo ^{[18
]}

Tan, Lei ^{[19
]}

Li, Fujian ^{[20
]}

Zheng, Chao ^{[21
]}

Liu, Hongwei ^{[3
]}

Li, Xinjie ^{[4
]}

Ertai, A. ^{[5
]}

Du, Yingrong ^{[6
]}

Liu, Fenglin ^{[7
]}

Cui, Wenyu ^{[9
]}

Wang, Quanhong ^{[10
]}

Chen, Xiaohong ^{[11
]}

Han, Junfeng ^{[12
]}

Xie, Qingyao ^{[13
]}

Feng, Yanmei ^{[14
]}

Liu, Wenyu ^{[15
]}

Tang, Peijun ^{[16
]}

Zhang, Jianyong ^{[17
]}

Zheng, Jian ^{[18
]}

Chen, Dawei ^{[20
]}

Yao, Xiangyang ^{[21
]}

Ren, Tong ^{[3
]}

Li, Yang ^{[4
]}

Li, Yuanyuan ^{[5
]}

Wu, Lei ^{[6
]}

Song, Qiang ^{[7
]}

Yang, Mei ^{[2
]}

Zhang, Jian ^{[9
]}

Liu, Yuanyuan ^{[12
]}

Guo, Shuliang ^{[14
]}

机构：

[1] Capital Med Univ, Beijing Chest Hosp, Beijing TB & Thorac Tumor Res Inst, Beijing 101149, Peoples R China

[2] Chongqing Publ Hlth Med Ctr, 109 Baoyu Rd, Chongqing 400036, Peoples R China

[3] Shenyang Chest Hosp, 11 Beihai St, Shenyang 110044, Peoples R China

[4] Guang Zhou Chest Hosp, 62 Heng Zhi Gang Rd, Guangzhou 510095, Guangdong, Peoples R China

[5] Chest Hosp Xinjiang, 106 Yan An Rd, Urumqi 830049, Xinjiang, Peoples R China

[6] Third Peoples Hosp Kunming, 319 Wu Jing Rd, Kunming 650041, Yunnan, Peoples R China

[7] Shandong Prov Chest Hosp, 12 Lieshishandong Rd, Jinan 250000, Shandong, Peoples R China

[8] Jiangxi Chest Third People Hosp, 346 Dieshan Rd, Nanchang 330006, Jiangxi, Peoples R China

[9] Chang Chun Infect Dis Hosp, 2699 Sandao Sect, Changchun 130123, Jilin, Peoples R China

[10] Taiyuan Fourth Peoples Hosp, 231 Xikuang St, Taiyuan 030024, Shanxi, Peoples R China

[11] Fuzhou Pulm Hosp Fujian, 2 Lakeside, Fuzhou 350008, Peoples R China

[12] Tianjin Haihe Hosp, 890 Shuanggangzhenjingu Rd, Tianjin 300350, Peoples R China

[13] Third Peoples Hosp Shenzhen, 29 Bulan Rd, Shenzhen 518112, Peoples R China

[14] Chongqing Med Univ, Affiliated Hosp 1, 1 Youyi Rd, Chongqing, Peoples R China

[15] Weifang 2 Peoples Hosp, 7th Yuanxiao St, Weifang 261041, Peoples R China

[16] Fifth Peoples Hosp Suzhou, 10 Guangqian Rd, Suzhou 215000, Jiangsu, Peoples R China

[17] Zunyi Med Coll, Affiliated Hosp, 149 Delian Rd, Zunyi 563000, Guizhou, Peoples R China

[18] Fifth Peoples Hosp Wuxi, 1215 GuangRui Rd, Wuxi 214001, Jiangsu, Peoples R China

[19] TB Hosp Siping City, 10 Dongshan Rd, Siping City 136001, Jilin, Peoples R China

[20] Baoding Hosp Infect Dis, 608 Dongfeng East Rd, Baoding City 071000, Hebei, Peoples R China

[21] Xiamen Univ, Affiliated 1, Xiamen, Fujian, Peoples R China

来源：

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 2021年 / 40卷 / 04期

关键词：

Comorbidity; Pulmonary tuberculosis; Prevalence; Risk; RESISTANT TUBERCULOSIS; DIABETES-MELLITUS; LUNG-CANCER; NATIONWIDE; SOUTHWEST;

D O I：

10.1007/s10096-020-04077-2

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

In clinical practice, PTB patients have concurrent many types of comorbidities such as pneumonia, liver disorder, diabetes mellitus, hematological disorder, and malnutrition. Detecting and treating specific comorbidities and preventing their development are important for PTB patients. However, the prevalence of most comorbid conditions in patients with PTB is not well described. We conducted a large-scale, multicenter, observational study to elucidate and illustrate the prevalence rates of major comorbidities in inpatients at 21 hospitals in China. The 19 specific comorbidities were selected for analysis in this patient cohort, and stratified the inpatient cohort according to age and gender. A total of 355,929 PTB inpatients were included, with a male:female ratio of 1.98 and the proportion of >= 65 years PTB inpatients was the most. Approximately 70% of PTB inpatients had at least one defined type of comorbidity. The prevalence of 19 specific comorbidities in inpatients with PTB was analyzed, with pneumonia being the most common comorbidity. The prevalence of most comorbidities was higher in males with PTB except thyroid disorders, mental health disorders, etc. The prevalence of defined most comorbidities in patients with PTB tended to increase with increasing age, although some specific comorbidities tended to increase initially then decrease with increasing age. Our study describes multiple clinically important comorbidities among PTB inpatients, and their prevalence between different gender and age groups. The results will enhance the clinical aptitude of physicians who treat patients with PTB to recognize, diagnose, and treat PTB comorbidities early.

引用

页码：787 / 800

页数：14

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