Danaparoid for cardiopulmonary bypass in patients with previous heparin-induced thrombocytopenia

被引：17
作者：
Gillis, S
Merin, G
Zahger, D
Deeb, M
Drenger, B
Hyam, E
Eldor, A
机构：
[1] HADASSAH UNIV HOSP,MED CTR,DEPT CARDIOTHORAC SURG,IL-91120 JERUSALEM,ISRAEL
[2] HADASSAH UNIV HOSP,MED CTR,DEPT ANAESTHESIOL,IL-91120 JERUSALEM,ISRAEL
[3] HADASSAH UNIV HOSP MT SCOPUS,CORONARY CARE UNIT,JERUSALEM,ISRAEL
[4] TEL AVIV MED CTR & SCH MED,HAEMATOL INST,TEL AVIV,ISRAEL
来源：
BRITISH JOURNAL OF HAEMATOLOGY | 1997年 / 98卷 / 03期
关键词：
danaparoid; cardiopulmonary bypass; heparin; thrombocytopenia;
D O I：
10.1046/j.1365-2141.1997.2633080.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Anticoagulation for cardiopulmonary bypass in patients with heparin-induced thrombocytopenia requires the use of other anticoagulants, We report a case in whom this was achieved using the heparinoid danaparoid (Orgaran). Based on our experience and a review of the literature, we provide guidelines for managing these rare patients. A danaparoid dose substantially lower than that recommended by the manufacturer may minimize bleeding complications.
引用
收藏
页码：657 / 659
页数：3
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