Regioselective acylation at the 5-or 6-position of L-tryptophan derivatives

被引：6
作者：
Jiang, YW
Ma, DW [1 ]
机构：
[1] Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Bioorgan & Nat Prod Chem, Shanghai 200032, Peoples R China
来源：
TETRAHEDRON LETTERS | 2002年 / 43卷 / 39期
基金：
中国国家自然科学基金;
关键词：
D O I：
10.1016/S0040-4039(02)01580-0
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The reaction of 1-acyl tryptophan derivatives with chloroacetyl chloride or the reaction of 1-tosyl tryptophan derivatives with acetyl chloride provides the corresponding 6-acylation products, while acylation of the 3-oxo tryptophan derivative gives a 5-substituted product. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：7013 / 7015
页数：3
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