Imaging Glioblastoma Posttreatment Progression, Pseudoprogression, Pseudoresponse, Radiation Necrosis

被引:28
作者
Strauss, Sara B. [1 ]
Meng, Alicia [1 ]
Ebani, Edward J. [1 ]
Chiang, Gloria C. [1 ]
机构
[1] Weill Cornell Med Ctr, Dept Radiol, 525 East 68th St,Box 141, New York, NY 10065 USA
关键词
Glioblastoma; Pseudoprogression; Pseudoresponse; Radiation necrosis; MAGNETIC-RESONANCE-SPECTROSCOPY; HIGH-GRADE GLIOMAS; POSITRON-EMISSION-TOMOGRAPHY; CEREBRAL BLOOD-VOLUME; MGMT PROMOTER METHYLATION; APPARENT DIFFUSION-COEFFICIENT; TREATMENT RESPONSE EVALUATION; NEWLY-DIAGNOSED GLIOBLASTOMA; RECURRENT MALIGNANT GLIOMAS; PRIMARY BRAIN-TUMOR;
D O I
10.1016/j.nic.2020.09.010
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Radiographic monitoring of posttreatment glioblastoma is important for clinical trials and determining next steps in management. Evaluation for tumor progression is confounded by the presence of treatment-related radiographic changes, making a definitive determination less straight-forward. The purpose of this article was to describe imaging tools available for assessing treatment response in glioblastoma, as well as to highlight the definitions, pathophysiology, and imaging features typical of true progression, pseudoprogression, pseudoresponse, and radiation necrosis. © 2020 Elsevier Inc.
引用
收藏
页码:103 / 120
页数:18
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