Transition-Metal-Free C-S Bond Formation: A Facile Access to Aryl Sulfones from Sodium Sulfinates via Arynes

被引：104

作者：

Pandya, Virat G. ^{[1
]}

Mhaske, Santosh B. ^{[1
]}

机构：

[1] CSIR Natl Chem Lab, Div Organ Chem, Pune 411008, Maharashtra, India

来源：

ORGANIC LETTERS | 2014年 / 16卷 / 14期

关键词：

THIA-FRIES REARRANGEMENT; BIOLOGICAL-ACTIVITY; CATALYZED SYNTHESIS; DIARYL SULFONES; INHIBITORS; ARYLATION; SALTS; SULFONYLATION; DERIVATIVES; TRIFLATE;

D O I：

10.1021/ol5018646

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Sulfones have been attractive targets for synthetic organic chemists owing to their immense applications in medicinal, material, and synthetic chemistry. In this context, an efficient transition-metal-free process has been demonstrated, wherein a broad range of alkyl/aryl/heteroaryl sodium sulfinates react with varyingly substituted aryne precursors (o-silyl aryl triflates) under mild reaction conditions to afford structurally diverse sulfones in good to excellent yields.

引用

页码：3836 / 3839

页数：4

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