A case of uncontrolled severe asthma patient with coexisting carcinoid tumor presenting as pneumomediastinum

被引:3
作者
Bicer, Elif Nur [1 ]
Ozturk, Ayse Bilge [2 ]
Ozyigit, Leyla Pur [3 ]
Erus, Suat [4 ]
Tanju, Serhan [5 ]
Dilege, Sukru [5 ]
Tabak, Levent [6 ]
机构
[1] Koc Univ, Sch Med, Istanbul, Turkey
[2] Koc Univ Hosp, Dept Allergy & Immunol, TR-34010 Istanbul, Turkey
[3] Koc Univ, Sch Med, Dept Allergy & Immunol, Istanbul, Turkey
[4] Koc Univ Hosp, Dept Thorac Surg, Istanbul, Turkey
[5] Koc Univ, Dept Thorac Surg, Sch Med, Istanbul, Turkey
[6] Koc Univ, Dept Pulm Med, Sch Med, Istanbul, Turkey
关键词
Carcinoid tumor; severe asthma; pneumomediastinum;
D O I
10.3109/02770903.2015.1054402
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Introduction: Patients with inadequately controlled or uncontrolled asthma are at a greater risk of attacks for asthma requiring emergency room visits or hospital admissions. There is a significant correlation between the severity of the disease and the severity of exacerbations. Patients with poorly controlled asthma are at a higher risk for complications. Case study: We present a 24-year-old aspirin-intolerant, uncontrolled asthma patient with the complication of pneumomediastinum. Results: Severe symptoms persisted after the resolution of the pneumomediastinum despite intense anti-inflammatory and anti-obstructive therapy. A bronchoscopy revealed an endobronchial lesion and she was diagnosed with a carcinoid tumor. Conclusion: This case is an example of the importance of re-evaluating asthma patients who do not respond to standard medical treatment. Clinicians should be aware of the complications associated with asthma attacks such as pneumomediastinum and the possibility of a differential diagnosis that worsen asthma symptoms such as a carcinoid tumor.
引用
收藏
页码:1095 / 1098
页数:4
相关论文
共 10 条
[1]  
[Anonymous], 1995, Global Strategy for Asthma Management and Prevention
[2]   Pneumomediastinum: Old signs and new signs [J].
Bejvan, SM ;
Godwin, JD .
AMERICAN JOURNAL OF ROENTGENOLOGY, 1996, 166 (05) :1041-1048
[3]   Surgical management of bronchial carcinoid tumors: 11-year experience [J].
Dadas, Erdogan ;
Tanju, Serhan ;
Ozkan, Berker ;
Bayrak, Yusuf ;
Kaba, Erkan ;
Dilege, Sukru ;
Toker, Alper .
TURK GOGUS KALP DAMAR CERRAHISI DERGISI-TURKISH JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2014, 22 (04) :795-799
[4]  
Dajer-Fadel Walid L, 2014, Asian Cardiovasc Thorac Ann, V22, P997, DOI 10.1177/0218492313504091
[5]   Design and baseline characteristics of The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study: a large cohort of patients with severe or difficult-to-treat asthma [J].
Dolan, CM ;
Fraher, KE ;
Bleecker, ER ;
Borish, L ;
Chipps, B ;
Hayden, ML ;
Weiss, S ;
Zheng, BY ;
Johnson, C ;
Wenzel, S .
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2004, 92 (01) :32-39
[6]   Pulmonary carcinoid - Presentation, diagnosis, and outcome in 142 cases in Israel and review of 640 cases from the literature [J].
Fink, G ;
Krelbaum, T ;
Yellin, A ;
Bendayan, D ;
Saute, M ;
Glazer, M ;
Kramer, MR .
CHEST, 2001, 119 (06) :1647-1651
[7]   What can predict the exacerbation severity in asthma? [J].
Oguzulgen, I. Kivilcim ;
Turktas, Haluk ;
Mullaoglu, Sema ;
Ozkar, Secil .
ALLERGY AND ASTHMA PROCEEDINGS, 2007, 28 (03) :344-347
[8]   (Correcting) misdiagnoses of asthma: a cost effectiveness analysis [J].
Pakhale, Smita ;
Sumner, Amanda ;
Coyle, Douglas ;
Vandemheen, Katherine ;
Aaron, Shawn .
BMC PULMONARY MEDICINE, 2011, 11
[9]   Pneumothorax and asthma [J].
Porpodis, Konstantinos ;
Zarogoulidis, Paul ;
Spyratos, Dionysios ;
Domvri, Kalliopi ;
Kioumis, Ioannis ;
Angelis, Nikolaos ;
Konoglou, Maria ;
Kolettas, Alexandros ;
Kessisis, Georgios ;
Beleveslis, Thomas ;
Tsakiridis, Kosmas ;
Katsikogiannis, Nikolaos ;
Kougioumtzi, Ioanna ;
Tsiouda, Theodora ;
Argyriou, Michael ;
Kotsakou, Maria ;
Zarogoulidis, Konstantinos .
JOURNAL OF THORACIC DISEASE, 2014, 6 :S152-S161
[10]  
Zahid M, 2011, BMJ CASE REP, V26, P2011