"Strawberry like" gingivitis being the first sign of Wegener's granulomatosis

被引:34
作者
Ruokonen, Hellevi [2 ]
Helve, Tapani [3 ]
Arola, Johanna [1 ]
Hietanen, Jarkko [2 ,4 ,5 ]
Lindqvist, Christian [2 ]
Hagstrom, Jaana [1 ]
机构
[1] Univ Helsinki, Dept Pathol, Haartman Inst, FIN-00014 Helsinki, Finland
[2] Univ Helsinki, Cent Hosp, Dept Oral & Maxillofacial Dis, FIN-00014 Helsinki, Finland
[3] Univ Helsinki, Cent Hosp, Dept Internal Med, Div Rheumatol,HUS, FIN-00014 Helsinki, Finland
[4] Univ Helsinki, Dept Oral Pathol, Inst Dent, FIN-00014 Helsinki, Finland
[5] Univ Helsinki, Cent Hosp, HUSLAB, FIN-00014 Helsinki, Finland
关键词
Wegener; Gingivitis; Granulomatous disease; Vasculitis; ORAL MANIFESTATIONS;
D O I
10.1016/j.ejim.2009.04.007
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Wegener's granulomatosis (WG) is a rare granulomatous necrotizing vasculitis of small vessels, affecting vascular structures having predilection for upper airways. If untreated WG can be lethal. WG is also known to cause oral mucosal lesions. We report a case of WC that was first diagnosed on oral gingival mucosa. A 51-year old woman was referred to a specialized dentist because of consistent irritative buccal gingival hyperplasia that did not react to conservative and microbial treatment. The lesion was biopsied and the diagnosis was suggestive for WG. Patient was further referred to the Department of Rheumatology and the diagnose of WG was confirmed and treated. The oral lesions cured totally. This case emphasizes the importance to recognize the oral manifestation of WG to get proper medication as soon as possible and avoid serious systemic tissue damage. (C) 2009 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:651 / 653
页数:3
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