Bacteriophage therapy for the treatment of infections

被引:0
作者
Gorski, Andrzej [1 ,2 ]
Miedzybrodzki, Ryszard [1 ]
Borysowski, Jan [2 ]
Weber-Dabrowska, Beata [1 ]
Lobocka, Malgorzata [3 ,4 ]
Fortuna, Wojciech [1 ]
Letkiewicz, Slawomir [1 ]
Zimecki, Michal
Filby, Grace [5 ]
机构
[1] Polish Acad Sci, Phage Therapy Unit, L Hirszfeld Inst Immunol & Expt Therapy, Dept Expt Therapy, PL-53114 Wroclaw, Poland
[2] Med Acad Warsaw, Inst Transplantat, Dept Clin Immunol, PL-02006 Warsaw, Poland
[3] Polish Acad Sci, Inst Biochem & Biophys, Dept Microbial Biochem, PL-02106 Warsaw, Poland
[4] Warsaw Univ Life Sci, Dept Microbial Biol, Fac Agr & Biol, PL-02766 Warsaw, Poland
[5] Designs Wellbeing, Reigate RH2 7JE, England
关键词
Antibiotic resistance; bacteria; MRSA; multidrug resistance; phage therapy; SUPPURATIVE BACTERIAL-INFECTIONS; ESCHERICHIA-COLI; STAPHYLOCOCCUS-AUREUS; PHAGE THERAPY; IN-VIVO; LISTERIA-MONOCYTOGENES; GENOMIC ANALYSIS; GENE-TRANSFER; PHI-KZ; MICE;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Increasing levels of antibiotic resistance constitutes one of the main challenges in medicine today, and has increased interest in the potential use of alternative antibacterial agents. One of the most interesting 'classes' of novel antibacterials used to combat multidrug-resistant bacteria is bacteriophages, which are viruses that specifically infect and kill bacterial cells. This review discusses the current status of bacteriophage therapy, including the experience of one expert center specializing in this form of treatment.
引用
收藏
页码:766 / 774
页数:9
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