Stem Cell Isolation from Human Wharton's Jelly: A Study of Their Differentiation Ability into Lens Fiber Cells

被引：0
作者：
Khatami, Seyedeh Mahsa [1 ]
Zahri, Saber [1 ]
Maleki, Masoud [2 ]
Hamidi, Kamaloddin [1 ]
机构：
[1] Univ Mohaghegh Ardabili, Fac Sci, Cell & Mol Lab, Dept Biol, Ardebil, Iran
[2] Islamic Azad Univ, East Azarbaijan Sci & Res Branch, Dept Biol, Tabriz, Iran
来源：
CELL JOURNAL | 2014年 / 15卷 / 04期
关键词：
Wharton's jelly; Mesenchymal Stem Cells; Crystallin; Differentiation; HUMAN UMBILICAL-CORD; GROWTH-FACTOR; IN-VITRO; EPITHELIAL-CELLS; EXPRESSION; CRYSTALLINS; GENERATION;
D O I：
暂无
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Recently, the use of stem cells has expanded into numerous areas including cell therapy. In this study, we investigated the differentiation capacity of human Wharton's jelly stem cells (hWJSCs) into lens fiber cells. Morphological changes and expressions of four crystallin genes (alpha A, alpha B, beta B1 and beta B3) were studied. The bovine vitreous body has been shown to induce expression of crystallin genes in hWJSCs. By using the vitreous as a lens fiber cell inducer, we showed that alpha B-, beta B1- and beta B3-crystallin genes expressed in hWJSCs.
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页码：364 / 371
页数：8
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