Synthetic Approaches and Biological Activities of 4-Hydroxycoumarin Derivatives

被引：122
作者：
Jung, Jae-Chul [2 ,3 ]
Park, Oee-Sook [1 ]
机构：
[1] Chungbuk Natl Univ, Coll Nat Sci, Inst Basic Sci, Dept Chem, Cheongju 361763, Chungbuk, South Korea
[2] Ewha Womans Univ, Sch Med, Med Res Inst, Seoul 158710, South Korea
[3] Ewha Womans Univ, Sch Med, BK21, Seoul 158710, South Korea
来源：
MOLECULES | 2009年 / 14卷 / 11期
关键词：
4-hydroxycoumarin; anticoagulant; rodenticide; ring cyclization; tetralone; coupling reaction; 2ND-GENERATION ANTICOAGULANT; PHARMACOLOGICAL ASSESSMENT; NAD(P)H-QUINONE REDUCTASE; CONDENSATION PRODUCTS; EFFICIENT SYNTHESIS; COUMARIN; WARFARIN; DICOUMAROL; ANTIBACTERIAL; DIPHENACOUM;
D O I：
10.3390/molecules14114790
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The main purpose of this review is to summarize recent chemical syntheses and structural modifications of 4-hydroxycoumarin and its derivatives, of interest due to their characteristic conjugated molecular architecture and biological activities.
引用
收藏
页码：4790 / 4803
页数：14
相关论文
共 51 条
[1]  
ADAMI E, 1959, Arch Ital Sci Farmacol, V9, P61
[2]   PHOTOAFFINITY INHIBITION OF RAT-LIVER NAD(P)H DEHYDROGENASE BY 3-(ALPHA-ACETONYL-PARA-AZIDOBENZYL)-4-HYDROXYCOUMARIN [J].
ALMEDA, S ;
BING, DH ;
LAURA, R ;
FRIEDMAN, PA .
BIOCHEMISTRY, 1981, 20 (13) :3731-3737
[3]  
Au N, 2008, DRUG METAB REV, V40, P355, DOI [10.1080/03602530801952187, 10.1080/03602530801952187 ]
[4]  
BEIER AP, 1999, MED PARAZITOL MOSK, V2, P40
[5]   Improved synthesis of some hydroxycoumarins [J].
Bulut, M ;
Erk, C .
DYES AND PIGMENTS, 1996, 30 (02) :99-104
[6]   Administration of dicoumarin compound for prophylaxis of postoperative thrombosis and embolism - A preliminary report [J].
Butsch, WL ;
Stewart, JD .
ARCHIVES OF SURGERY, 1942, 45 (04) :551-553
[7]  
Chaudhary V, 2006, INDIAN J AGR SCI, V76, P736
[8]   Design and synthesis of novel diphenacoum-derived, conformation-restricted vitamin K 2,3-epoxide reductase inhibitors [J].
Chen, DU ;
Kuo, PY ;
Yang, DY .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2005, 15 (10) :2665-2668
[9]  
Chiarino D., 1988, Eur. Pat. Appl., Patent No. 284017
[10]   Antibacterial, antifungal and cytotoxic properties of novel N-substituted sulfonamides from 4-hydroxycoumarin [J].
Chohan, Zahid H. ;
Shaikh, Ali U. ;
Rauf, Abdul ;
Supuran, Claudiu T. .
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2006, 21 (06) :741-748
123456