Neighborhood and HIV infection among IDU: Place of residence independently predicts HIV infection among a cohort of injection drug users

被引:80
作者
Maas, Benjamin
Fairbairn, Nadia
Kerr, Thomas
Li, Kathy
Montaner, Julio S. G.
Wood, Evan
机构
[1] British Columbia Centre for Excellence in HIV, AIDS, St. Paul's Hospital
[2] Department of Medicine, University of British Columbia
关键词
HIV; IDU; risk environment; neighborhood; Vancouver;
D O I
10.1016/j.healthplace.2006.05.005
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
This study was undertaken to investigate geographic residence in Vancouver's Downtown Eastside (DTES), Canada's poorest urban neighborhood, as an environmental risk factor for HIV infection among a cohort of injection drug users. HIV incidence rates were examined using Kaplan-Meier methods, and Cox proportional hazards regression was used to determine independent risk factors for HIV seroconversion. After intensive multivariate adjustment, DTES residence remained an independent predictor of HIV seroconversion (relative hazard =2.0, 95% CI: 1.4-3.0, p < 0.001). These findings indicate the need for a greater recognition among policy-makers of geographic location as a risk factor for HIV incidence in urban settings and the need for further research to determine why place contributes so greatly to HIV risk. The findings also mark a need for prevention interventions to be appropriately targeted towards high-risk neighborhoods. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码:432 / 439
页数:8
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