Elasticity measurements in scarred rabbit vocal folds using air pulse stimulation

被引：12

作者：

Hertegard, Stellan ^{[1
]}

Larsson, Hans ^{[1
]}

Nagubothu, Srinivasa S. R. ^{[2
]}

Tolf, Anna ^{[3
]}

Svensson, Bengt ^{[4
]}

机构：

[1] Karolinska Univ, Huddinge Hosp, Karolinska Inst, Dept Logoped & Phoniatr, SE-14186 Stockholm, Sweden

[2] Karolinska Inst, Dept Woman & Child Hlth, S-10401 Stockholm, Sweden

[3] Karolinska Univ, Huddinge Hosp, Dept Pathol, SE-14186 Stockholm, Sweden

[4] Ostersund Hosp, Dept Otorhinolaryngol, Stockholm, Sweden

来源：

LOGOPEDICS PHONIATRICS VOCOLOGY | 2009年 / 34卷 / 04期

关键词：

Air pulse stimulation; elasticity; vocal fold scarring; CANINE MODEL; FOLLOW-UP; INJECTION;

D O I：

10.3109/14015430902913527

中图分类号：

R36 [病理学]; R76 [耳鼻咽喉科学];

学科分类号：

100104 ; 100213 ;

摘要：

This study aimed to compare vocal fold elasticity data from a new method for non-invasive analysis by stimulations of the mucosa with short air pulses. The depth of the mucosal deflections is measured with laser pulses by means of a special algorithm. Ten scarred New Zealand rabbit vocal folds and four normal rabbit folds were measured directly after sacrifice. The elastic data were compared to histological sections from the scarred vocal folds analysed by a pathologist. The results showed significantly lower elasticity (higher stiffness) values for the more scarred vocal folds as compared to samples with minor damage (P = 0.03). It is concluded that the air pulse stimulation method is a promising tool for non-invasive quantification of vocal fold scarring.

引用

页码：190 / 195

页数：6

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