Optimal number of EUS-guided fine needle passes needed to obtain a correct diagnosis

被引:221
作者
LeBlanc, JK [1 ]
Ciaccia, D [1 ]
Al-Assi, MT [1 ]
McGrath, K [1 ]
Imperiale, T [1 ]
Tao, LC [1 ]
Vallery, S [1 ]
DeWitt, J [1 ]
Sherman, S [1 ]
Collins, E [1 ]
机构
[1] Indiana Univ, Med Ctr, Indianapolis, IN 46202 USA
关键词
D O I
10.1016/S0016-5107(03)02863-3
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background., The immediate assistance of a cytologist during EUS-guided FNA is not universal. The optimal number of fine needle passes during EUS-guided FNA has not been determined in a prospective study. The aim of this study was to determine the optimal number of passes required to obtain a correct diagnosis. Methods: Seven or more passes were made with a fine needle into a variety of lesions during EUS-guided FNA. Adequacy of the aspirate, diagnosis, and a "certainty score" were recorded after each pass and interpreted sequentially by a cytopathologist. Surgical histopathology and 1-year clinical follow-up were used as reference standards. The percentage of correctly diagnosed cases was calculated and stratified according to organ, disease group, and EUS characteristics of the lesion. Results: Lesions from 95 patients were categorized into the following locations: pancreas, lymph node, and miscellaneous. The sensitivity and specificity for 7 passes from the pancreas and miscellaneous lesion groups were, respectively, 83% and 100%. The sensitivity and specificity for 5 passes from the lymph node group were, respectively, 77% and 100%. Conclusions: During EUS-guided FNA, at least 7 passes with a fine needle into pancreatic and miscellaneous lesions, and 5 passes into lymph nodes are needed to ensure a high degree of certainty for making a correct diagnosis.
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页码:475 / 481
页数:7
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