Recognition of Mismatched Base Pairs in DNA

被引:44
作者
Nakatani, Kazuhiko [1 ]
机构
[1] Osaka Univ, Inst Sci & Ind Res, Osaka 5670047, Japan
关键词
GUANINE-GUANINE MISMATCHES; HUMAN TELOMERIC SEQUENCE; NAPHTHYRIDINE DIMER; HUMAN-CHROMOSOMES; MOLECULAR GLUE; BINDING; REPEAT; BULGE; FORM; POLYMORPHISM;
D O I
10.1246/bcsj.82.1055
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Mismatch binding ligand (MBL) selectively binds to mismatched base pairs with discrimination of the nucleotide bases composing the mismatch. This review focuses on the inside story regarding the molecular design of MBL and its function, and potential application in genomic science.
引用
收藏
页码:1055 / 1069
页数:15
相关论文
共 68 条
  • [11] Molecular recognition of DNA by small molecules
    Dervan, PB
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2001, 9 (09) : 2215 - 2235
  • [12] Photoswitchable molecular glue for DNA
    Dohno, Chikara
    Uno, Shin-Nosuke
    Nakatani, Kazuhiko
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129 (39) : 11898 - +
  • [13] GACY AM, 1995, CELL, V81, P533
  • [14] Analysis of mismatched DNA by mismatch binding ligand (MBL)-Sepharose affinity chromatography
    Goto, Yuki
    Suda, Hitoshi
    Kobori, Akio
    Nakatani, Kazuhiko
    [J]. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2007, 388 (5-6) : 1165 - 1173
  • [15] Small-molecule binding to the nonquadruplex form of the human telomeric sequence
    Goto, Yuki
    Hagihara, Shinya
    Hagihara, Masaki
    Nakatani, Kazuhiko
    [J]. CHEMBIOCHEM, 2007, 8 (07) : 723 - 726
  • [16] Telomere length regulation
    Greider, CW
    [J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1996, 65 : 337 - 365
  • [17] Ligand-stabilized hairpin structures interfere with elongation of human telomere
    Hagihara, Masaki
    Goto, Yuki
    Nakatani, Kazuhiko
    [J]. CHEMBIOCHEM, 2008, 9 (04) : 510 - 513
  • [18] Detection of guanine-adenine mismatches by surface plasmon resonance sensor carrying naphthyridine-azaquinolone hybrid on the surface
    Hagihara, S
    Kumasawa, H
    Goto, Y
    Hayashi, G
    Kobori, A
    Saito, I
    Nakatani, K
    [J]. NUCLEIC ACIDS RESEARCH, 2004, 32 (01) : 278 - 286
  • [19] A DNA polymerase stop assay for G-quadruplex-interactive compounds
    Han, HY
    Hurley, LH
    Salazar, M
    [J]. NUCLEIC ACIDS RESEARCH, 1999, 27 (02) : 537 - 542
  • [20] Intercalative G-tetraplex stabilization of telomeric DNA by a cationic porphyrin
    Haq, I
    Trent, JO
    Chowdhry, BZ
    Jenkins, TC
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (09) : 1768 - 1779