[3+2] Cycloaddition of 3-Diazooxindole with Arynes for the Synthesis of Spiro[indazole-3,3′-indolin]-2′-ones

被引：8

作者：

Reddy, Basi V. Subba ^{[1
]}

Reddy, Raveendra Reddy Gopi ^{[1
,2
]}

Thummaluru, Veera Reddy ^{[2
]}

Sridhar, Balasubramanian ^{[3
]}

机构：

[1] CSIR Indian Inst Chem Technol, Ctr Semiochem, Hyderabad 500007, Andhra Pradesh, India

[2] Vikrama Simhapuri Univ, Dept Chem, Nellore 524003, Andhra Pradesh, India

[3] CSIR Indian Inst Chem Technol, Lab Xray Crystallog, Hyderabad 500007, Andhra Pradesh, India

来源：

CHEMISTRYSELECT | 2017年 / 2卷 / 15期

关键词：

Benzyne; Cesium fluoride; Cycloaddition; 3-Diazooxindoles; Spiroindazoles; ALPHA-DIAZOCARBONYL COMPOUNDS; ORGANIC-SYNTHESIS; OXINDOLES; KETIMINES; INDOLES; BENZYNE; SERIES;

D O I：

10.1002/slct.201700715

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An intermolecular cycloaddition between 3-diazooxindoles and arynes generated insitu from 2-(trimethylsilyl)phenyltrifluoromethanesulfonate in the presence of 2.5mol% cesium fluoride has been achieved to produce a novel series of spiro[indazole-3,3'-indolin]-2'-one derivatives in good yields under mild experimental conditions. It is an elegant strategy for the quick construction of a highly rigid spirocyclic compounds in a single step.

引用

页码：4290 / 4293

页数：4

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