Preferred interparticle spacings in trains of particles in inertial microchannel flows

被引:70
作者
Kahkeshani, Soroush [1 ]
Haddadi, Hamed [1 ]
Di Carlo, Dino [1 ]
机构
[1] Univ Calif Los Angeles, Calif NanoSyst Inst, Dept Bioengn, Los Angeles, CA 90095 USA
关键词
microfluidics; micro-/nano-fluid dynamics; suspensions; DISCRETIZED BOLTZMANN-EQUATION; PARTICULATE SUSPENSIONS; POISEUILLE FLOW; NUMERICAL SIMULATIONS; REYNOLDS-NUMBER; MIGRATION;
D O I
10.1017/jfm.2015.678
中图分类号
O3 [力学];
学科分类号
08 ; 0801 ;
摘要
Suspended particles migrate towards inertial focusing positions close to walls and align into trains in finite inertia conduit flow. The relative contribution of inertial and viscous forces at the particle length scale, defined by the particle Reynolds number (Re-p), is a key parameter, where Re-p = <(gamma)over dot > D-2/nu depends on the mean shear rate <(gamma)over dot >, particle diameter D and fluid kinematic viscosity nu. Controlling the location of inertial focusing positions and the interparticle distance is critical in applications such as flow cytometry, imaging and cell entrapment in droplets. By using experimental observations in rectangular microcharmels and lattice Boltzmann numerical simulations of dilute suspension flow, the spacing between particles aligned in trains is measured. From the modes of the probability density function of interparticle spacing, preferred spacings at 5D and 2.5D are observed. At lower Re-p, the preferred spacing forms around 5D, and with increasing Re-p the spacing at 2.5D becomes more pronounced. With increasing concentration of the suspension the spacing is influenced by particle crowding effects until stable trains are no longer observed.
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页数:11
相关论文
共 26 条
[1]   Direct analysis of particulate suspensions with inertia using the discrete Boltzmann equation [J].
Aidun, CK ;
Lu, YN ;
Ding, EJ .
JOURNAL OF FLUID MECHANICS, 1998, 373 :287-311
[2]   Lattice-Boltzmann Method for Complex Flows [J].
Aidun, Cyrus K. ;
Clausen, Jonathan R. .
ANNUAL REVIEW OF FLUID MECHANICS, 2010, 42 :439-472
[3]   Inertial microfluidic physics [J].
Amini, Hamed ;
Lee, Wonhee ;
Di Carlo, Dino .
LAB ON A CHIP, 2014, 14 (15) :2739-2761
[4]   The inertial lift on a spherical particle in a plane Poiseuille flow at large channel Reynolds number [J].
Asmolov, ES .
JOURNAL OF FLUID MECHANICS, 1999, 381 :63-87
[5]   Inertial migration of neutrally buoyant particles in a square duct: An investigation of multiple equilibrium positions [J].
Chun, B ;
Ladd, AJC .
PHYSICS OF FLUIDS, 2006, 18 (03)
[6]   Galilean invariance in the lattice-Boltzmann method and its effect on the calculation of rheological properties in suspensions [J].
Clausen, Jonathan R. ;
Aidun, Cyrus K. .
INTERNATIONAL JOURNAL OF MULTIPHASE FLOW, 2009, 35 (04) :307-311
[7]  
Dendukuri D, 2007, LAB CHIP, V7, P818, DOI 10.1039/b703457a
[8]   Continuous inertial focusing, ordering, and separation of particles in microchannels [J].
Di Carlo, Dino ;
Irimia, Daniel ;
Tompkins, Ronald G. ;
Toner, Mehmet .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (48) :18892-18897
[9]   Inertial microfluidics [J].
Di Carlo, Dino .
LAB ON A CHIP, 2009, 9 (21) :3038-3046
[10]   Particle Segregation and Dynamics in Confined Flows [J].
Di Carlo, Dino ;
Edd, Jon F. ;
Humphry, Katherine J. ;
Stone, Howard A. ;
Toner, Mehmet .
PHYSICAL REVIEW LETTERS, 2009, 102 (09)