Risk of Hospitalized Falls and Hip Fractures in 22,103 Older Adults Receiving Mental Health Care vs 161,603 Controls: A Large Cohort Study

被引:24
作者
Stubbs, Brendon [1 ,2 ]
Perara, Gayan [2 ]
Koyanagi, Ai [3 ,4 ]
Veronese, Nicola [5 ]
Vancampfort, Davy [6 ,7 ]
Firth, Joseph [8 ,9 ]
Sheehan, Katie [10 ]
De Hert, Marc [11 ,12 ]
Stewart, Robert [1 ,2 ]
Mueller, Christoph [1 ,2 ]
机构
[1] South London & Maudsley NHS Fdn Trust, Denmark Hill, London SE5 8AZ, England
[2] Kings Coll London, Inst Psychiat Psychol & Neurosci IoPPN, London, England
[3] Univ Barcelona, Res & Dev Unit, Fundacio Sant Joan de Deu, CIBERSAM, Parc Sanitari St Joan de Deu, Barcelona, Spain
[4] ICREA, Barcelona, Spain
[5] Azienda ULSS Unita Locale Socio Sanit 3 Serenissi, Primary Care Dept, Venice, Italy
[6] Univ Leuven, KU Leuvene, Dept Rehabil Sci, Leuven, Belgium
[7] Univ Leuven, KU Leuven, Univ Psychiat Ctr, Kortenberg, Belgium
[8] Western Sydney Univ, NICM Hlth Res Inst, Sydney, NSW, Australia
[9] Univ Manchester, Fac Biol Med & Hlth, Div Psychol & Mental Hlth, Manchester, Lancs, England
[10] Kings Coll London, Sch Populat Hlth & Environm Sci, Dept Populat Hlth Sci, London, England
[11] Katholieke Univ Leuven, Univ Psychiat Ctr, Kortenberg, Belgium
[12] Univ Antwerp, Antwerp Hlth Law & Eth Chair, Antwerp, Belgium
基金
英国工程与自然科学研究理事会;
关键词
Hip fracture; falls dementia; mental illness; schizophrenia; substance use disorder; BIPOLAR DISORDER; PEOPLE; PREVALENCE; MULTIMORBIDITY; METAANALYSIS; COMORBIDITY; MORTALITY; ABUSE;
D O I
10.1016/j.jamda.2020.03.005
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Objectives: To investigate the risk of hospitalized fall or hip fracture among older adults using mental health services. Design: Retrospective cohort study. Setting and Participants: Residents of a South London catchment aged >60 years receiving specialist mental health care between 2008 and 2016. Measures: Falls and/or a hip fracture leading to hospitalization were ascertained from linked national records. Incidence rates and incidence rate ratios (IRRs) were age- and gender-standardized to the catchment population. Multivariable survival analyses were applied investigating falls and/or hip fractures as outcomes. Results: In 22,103 older adults, incidence rates were 60.1 per 1000 person-years for hospitalized falls and 13.7 per 1000 person-years for hip fractures, representing standardized IRRs of 2.17 [95% confidence interval (CI) 2.07-2.28] and 4.18 (3.79-4.60), respectively. The IRR for falls was high in those with substance-use disorder [IRR = 6.72 (5.35-8.33)], bipolar disorder [IRR = 3.62 (2.50-5.05)], depression [IRR = 2.28 (2.00-2.59)], and stress-related disorders [IRR = 2.57 (2.10-3.11)]. Hip fractures were increased in all populations (IRR > 2.5), with greatest risk in substance use disorders [IRR = 12.64 (7.2220.52)], dementia [IRR= 4.38 (3.82-5.00)], and delirium [IRR = 4.03 (3.00-5.29)]. Comparing mental disorder subgroups with each other, after the adjustment for 25 potential confounders, patients with dementia and substance use had a significantly increased risk of falls, and patients with dementia also had an increased risk of hip fractures. Conclusion and Implications: Older people using mental health services have more than double the incidence of falls and 4 times the incidence of hip fractures compared to the general population. Although incidences differ between diagnostic subgroups, all groups have a higher incidence than the general population. Targeted interventions to prevent falls and hip fractures among older adult mental health service users are urgently needed. (C) 2020 The Author(s). Published by Elsevier Inc. on behalf of AMDA - The Society for Post-Acute and Long-Term Care Medicine. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
引用
收藏
页码:1893 / 1899
页数:7
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