Solvent-free bromination of 1,3-diketones and β-keto esters with NBS

被引：60
作者：
Pravst, Igor
Zupan, Marko
Stavber, Stojan
机构：
[1] Univ Ljubljana, Fac Chem & Chem Technol, SI-1000 Ljubljana, Slovenia
[2] Jozef Stefan Inst, Organ & Bioorgan Chem Lab, SI-1000 Ljubljana, Slovenia
来源：
GREEN CHEMISTRY | 2006年 / 8卷 / 11期
关键词：
D O I：
10.1039/b608446j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Trituration of N-bromosuccinimide at room temperature with several liquid or solid 1,3-diketones and beta-keto esters resulted in high yield conversion to the monobrominated derivatives, and a work-up procedure using only water to remove succinimide was employed. The entire process uses no organic solvent and is therefore more ecologically desirable.
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页码：1001 / 1005
页数：5
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