C. sordellii lethal toxin-induced apoptotic cell death is based on inhibition of phosphoinositide-3 kinase Akt signalling

被引:0
|
作者
Schulz, F. [1 ]
Just, I [1 ]
Genth, H. [1 ]
机构
[1] Hannover Med Sch, Inst Toxikol, D-30623 Hannover, Germany
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
91
引用
收藏
页码:24 / 24
页数:1
相关论文
共 28 条
  • [1] Prevention of Clostridium sordellii Lethal Toxin-Induced Apoptotic Cell Death by Tauroursodeoxycholic Acid
    Schulz, Florian
    Just, Ingo
    Genth, Harald
    BIOCHEMISTRY, 2009, 48 (38) : 9002 - 9010
  • [2] Keratinocyte Growth Factor Protects Against C. difficile Toxin-Induced Injury, Cell Death and Apopotisis In Vitro and In Vivo
    Bau, Jason
    Alhassan, Basmah
    Roth, Jordan
    Jimmie Nguyen
    Harris, Xander
    Buie, Cameron
    Li, Annie
    Iablokov, Vadim
    MacNaughton, Wallace
    MacDonald, Justin
    Beck, Paul L.
    GASTROENTEROLOGY, 2016, 150 (04) : S816 - S817
  • [3] 3-Phosphoinositide-dependent protein kinase-1/Akt signalling and inhibition in a canine prostate carcinoma cell line
    Alvarez, F. J.
    Murahari, S.
    Couto, C. G.
    Rosol, T. J.
    Kulp, S. K.
    Chen, C.-S.
    Kisseberth, W. C.
    VETERINARY AND COMPARATIVE ONCOLOGY, 2007, 5 (01) : 47 - 58
  • [4] Mitochondrial proteins bnip3 and Bnip3L are involved in anthrax lethal toxin-induced macrophage cell death
    Ha, Soon-Duck
    Ng, Dennis
    Lamothe, Julie
    Valvano, Miguel A.
    Han, Jiahuai
    Kim, Sung Ouk
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (36) : 26275 - 26283
  • [5] Growth factor-induced phosphoinositide 3-OH kinase/Akt phosphorylation in smooth muscle cells: induction of cell proliferation and inhibition of cell death
    Jung, F
    Haendeler, J
    Goebel, C
    Zeiher, AM
    Dimmeler, S
    CARDIOVASCULAR RESEARCH, 2000, 48 (01) : 148 - 157
  • [6] Critical role of the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase-3β signaling pathway in recovery from anthrax lethal toxin-induced cell cycle arrest and MEK cleavage in macrophages
    Ha, Soon-Duck
    Ng, Dennis
    Pelech, Steven L.
    Kim, Sung Ouk
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (50) : 36230 - 36239
  • [7] Phosphoinositide 3-OH kinase/protein kinase B inhibits apoptotic cell death induced by reactive oxygen species in Saccharomyces cerevisiae
    Jeon, BW
    Kim, KT
    Chang, SI
    Kim, HY
    JOURNAL OF BIOCHEMISTRY, 2002, 131 (05): : 693 - 699
  • [8] Hydrogen peroxide in the Burkitt's lymphoma cell line Raji provides protection against arsenic trioxide-induced apoptosis via the phosphoinositide-3 kinase signalling pathway
    Lu, D
    Bai, XC
    Gui, L
    Su, YC
    Deng, F
    Liu, B
    Li, XM
    Zeng, WS
    Cheng, BL
    Luo, SQ
    BRITISH JOURNAL OF HAEMATOLOGY, 2004, 125 (04) : 512 - 520
  • [9] Inhibition of the PI3 kinase/Akt pathway enhances doxorubicin-induced apoptotic cell death in tumor cells in a p53-dependent manner
    Fujiwara, Y
    Kawada, K
    Takano, D
    Tanimura, S
    Ozaki, K
    Kohno, M
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2006, 340 (02) : 560 - 566
  • [10] Role of the PI3K/AKT signalling pathway in apoptotic cell death in the cerebral cortex of streptozotocin-induced diabetic rats
    Meng, Yan
    Wang, Weiwei
    Kang, Jinsong
    Wang, Xinxue
    Sun, Liankun
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2017, 13 (05) : 2417 - 2422