Chemical Stimulation of Aplysia californica Ganglion with Microfluidic Signal Generators

被引：1

作者：

Azizi, Farouk ^{[1
]}

Mastrangelo, Carlos H. ^{[1
]}

Lu, Hui ^{[2
]}

Chiel, Hillel J. ^{[2
]}

机构：

[1] Univ Utah, Dept Elect & Biomed Engn, Salt Lake City, UT 84112 USA

[2] Case Western Reserve Univ, Dept Biol Neurosci & Biomed Engn, Cleveland, OH USA

来源：

2008 IEEE BIOMEDICAL CIRCUITS AND SYSTEMS CONFERENCE - INTELLIGENT BIOMEDICAL SYSTEMS (BIOCAS) | 2008年

关键词：

D O I：

10.1109/BIOCAS.2008.4696935

中图分类号：

TP18 [人工智能理论];

学科分类号：

081104 ; 0812 ; 0835 ; 1405 ;

摘要：

We implemented a microfluidic signal generator chip for the in-vitro study of the nervous system of Aplysia californica under localized chemical stimulation. The PDMS chip implements a one-bit pulse-code modulator that digitally controls the concentration of the non-hydrolysable cholinergic agonist carbachol injected directly above a ganglion. The chip was successful in inducing a burst of ingestive patterns.

引用

页码：305 / +

页数：3

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