Influence of the cleaning temperature on the permeability of ceramic membranes

被引：29

作者：

Almecija, M. C. ^{[1
]}

Martinez-Ferez, A. ^{[1
]}

Guadix, A. ^{[1
]}

Paez, M. P. ^{[1
]}

Guadix, E. M. ^{[1
]}

机构：

[1] Univ Granada, Dept Chem Engn, Granada, Spain

来源：

DESALINATION | 2009年 / 245卷 / 1-3期

关键词：

Ceramic; Membrane; Chemical cleaning; Temperature; PERFORMANCE LIQUID-CHROMATOGRAPHY; WHEY-PROTEIN ISOLATE; POLYSTYRENE-DIVINYLBENZENE; ULTRAFILTRATION MEMBRANE; FRACTIONATION; SEPARATION; QUANTITATION;

D O I：

10.1016/j.desal.2009.02.041

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Membrane separation technologies applied to protein purification is an interesting development that has seen growth in recent years. However, studies about the long-term effects of the cleaning stage, considering different chemical agents and operating conditions, on the performance of the membranes are scarce in the literature. The purpose of this study was to evaluate experimentally the effect of a caustic-surfactant solution (the most commonly used for protein cleaning) at three different cleaning temperatures (30, 50 and 60 degrees C) upon a 300 kDa tubular ceramic membrane. To this end, 15 repeated fouling and cleaning cycles with a mixture of model proteins, beta-lactoglobulin and BSA, were performed. The cleaning temperature of 50 degrees C was found to be the optimal due to: (a) its capability to restore the permeability to the initial values after each operating cycle, (b) the higher yield regarding protein separation. A process of membrane pore erosion was found for the cleaning temperature of 60 degrees C.

引用

页码：708 / 713

页数：6

共 14 条

[1] Effect of pH on the fractionation of whey proteins with a ceramic ultrafiltration membrane [J].