共 49 条
Potential and Limitation of HLA-Based Banking of Human Pluripotent Stem Cells for Cell Therapy
被引:70
作者:

de Rham, Casimir
论文数: 0 引用数: 0
h-index: 0
机构: Univ Hosp Geneva, Transplant Immunol Unit, Div Immunol & Allergy, CH-1211 Geneva 14, Switzerland

Villard, Jean
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h-index: 0
机构:
Univ Hosp Geneva, Transplant Immunol Unit, Div Immunol & Allergy, CH-1211 Geneva 14, Switzerland Univ Hosp Geneva, Transplant Immunol Unit, Div Immunol & Allergy, CH-1211 Geneva 14, Switzerland
机构:
[1] Univ Hosp Geneva, Transplant Immunol Unit, Div Immunol & Allergy, CH-1211 Geneva 14, Switzerland
关键词:
NON-HODGKIN-LYMPHOMA;
TRANSPLANTATION;
DONOR;
LINES;
IMMUNOGENICITY;
INDUCTION;
MOLECULES;
NUMBER;
D O I:
10.1155/2014/518135
中图分类号:
R392 [医学免疫学];
Q939.91 [免疫学];
学科分类号:
100102 ;
摘要:
Great hopes have been placed on human pluripotent stem (hPS) cells for therapy. Tissues or organs derived from hPS cells could be the best solution to cure many different human diseases, especially those who do not respond to standard medication or drugs, such as neurodegenerative diseases, heart failure, or diabetes. The origin of hPS is critical and the idea of creating a bank of well-characterized hPS cells has emerged, like the one that already exists for cord blood. However, the main obstacle in transplantation is the rejection of tissues or organ by the receiver, due to the three main immunological barriers: the human leukocyte antigen (HLA), the ABO blood group, and minor antigens. The problem could be circumvented by using autologous stem cells, like induced pluripotent stem (iPS) cells, derived directly from the patient. But iPS cells have limitations, especially regarding the disease of the recipient and possible difficulties to handle or prepare autologous iPS cells. Finally, reaching standards of good clinical or manufacturing practices could be challenging. That is why well-characterized and universal hPS cells could be a better solution. In this review, we will discuss the interest and the feasibility to establish hPS cells bank, as well as some economics and ethical issues.
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共 49 条
[1]
Generation of pluripotent stem cells from adult mouse liver and stomach cells
[J].
Aoi, Takashi
;
Yae, Kojiro
;
Nakagawa, Masato
;
Ichisaka, Tomoko
;
Okita, Keisuke
;
Takahashi, Kazutoshi
;
Chiba, Tsutomu
;
Yamanaka, Shinya
.
SCIENCE,
2008, 321 (5889)
:699-702

Aoi, Takashi
论文数: 0 引用数: 0
h-index: 0
机构:
Kyoto Univ, Dept Stem Cell Biol, Inst Frontier Med Sci, Kyoto 6068507, Japan
Kyoto Univ, Dept Gastroenterol & Hepatol, Grad Sch Med, Kyoto 6068507, Japan Kyoto Univ, Dept Stem Cell Biol, Inst Frontier Med Sci, Kyoto 6068507, Japan

Yae, Kojiro
论文数: 0 引用数: 0
h-index: 0
机构:
Kyoto Univ, Dept Stem Cell Biol, Inst Frontier Med Sci, Kyoto 6068507, Japan Kyoto Univ, Dept Stem Cell Biol, Inst Frontier Med Sci, Kyoto 6068507, Japan

Nakagawa, Masato
论文数: 0 引用数: 0
h-index: 0
机构:
Kyoto Univ, Dept Stem Cell Biol, Inst Frontier Med Sci, Kyoto 6068507, Japan Kyoto Univ, Dept Stem Cell Biol, Inst Frontier Med Sci, Kyoto 6068507, Japan

Ichisaka, Tomoko
论文数: 0 引用数: 0
h-index: 0
机构:
Kyoto Univ, Dept Stem Cell Biol, Inst Frontier Med Sci, Kyoto 6068507, Japan
Japan Sci & Technol Agcy, CREST, Kawaguchi, Saitama 3320012, Japan Kyoto Univ, Dept Stem Cell Biol, Inst Frontier Med Sci, Kyoto 6068507, Japan

Okita, Keisuke
论文数: 0 引用数: 0
h-index: 0
机构:
Kyoto Univ, Dept Stem Cell Biol, Inst Frontier Med Sci, Kyoto 6068507, Japan Kyoto Univ, Dept Stem Cell Biol, Inst Frontier Med Sci, Kyoto 6068507, Japan

Takahashi, Kazutoshi
论文数: 0 引用数: 0
h-index: 0
机构:
Kyoto Univ, Dept Stem Cell Biol, Inst Frontier Med Sci, Kyoto 6068507, Japan Kyoto Univ, Dept Stem Cell Biol, Inst Frontier Med Sci, Kyoto 6068507, Japan

论文数: 引用数:
h-index:
机构:

Yamanaka, Shinya
论文数: 0 引用数: 0
h-index: 0
机构:
Kyoto Univ, Dept Stem Cell Biol, Inst Frontier Med Sci, Kyoto 6068507, Japan
Japan Sci & Technol Agcy, CREST, Kawaguchi, Saitama 3320012, Japan
Gladstone Inst Cardiovasc Dis, San Francisco, CA 94158 USA
Kyoto Univ, Ctr Induced Pluripotent StemiPS Cell Res & Applic, Inst Integrated Cell Mat Sci, Kyoto 6068507, Japan Kyoto Univ, Dept Stem Cell Biol, Inst Frontier Med Sci, Kyoto 6068507, Japan
[2]
Molecules and mechanisms of the graft-versus-leukaemia effect
[J].
Bleakley, M
;
Riddell, SR
.
NATURE REVIEWS CANCER,
2004, 4 (05)
:371-380

Bleakley, M
论文数: 0 引用数: 0
h-index: 0
机构:
Fred Hutchinson Canc Res Ctr, Seattle, WA 98109 USA Fred Hutchinson Canc Res Ctr, Seattle, WA 98109 USA

Riddell, SR
论文数: 0 引用数: 0
h-index: 0
机构:
Fred Hutchinson Canc Res Ctr, Seattle, WA 98109 USA Fred Hutchinson Canc Res Ctr, Seattle, WA 98109 USA
[3]
Immune Influence on Adult Neural Stem Cell Regulation and Function
[J].
Carpentier, Pamela A.
;
Palmer, Theo D.
.
NEURON,
2009, 64 (01)
:79-92

Carpentier, Pamela A.
论文数: 0 引用数: 0
h-index: 0
机构:
Stanford Univ, Dept Neurosurg, Stanford, CA 94305 USA Stanford Univ, Dept Neurosurg, Stanford, CA 94305 USA

Palmer, Theo D.
论文数: 0 引用数: 0
h-index: 0
机构:
Stanford Univ, Dept Neurosurg, Stanford, CA 94305 USA Stanford Univ, Dept Neurosurg, Stanford, CA 94305 USA
[4]
Tolerance strategies for stem-cell-based therapies
[J].
Chidgey, Ann P.
;
Layton, Daniel
;
Trounson, Alan
;
Boyd, Richard L.
.
NATURE,
2008, 453 (7193)
:330-337

Chidgey, Ann P.
论文数: 0 引用数: 0
h-index: 0
机构:
Monash Univ, Monash Immunol & Stem Cell Labs, STRIP, Clayton, Vic 3800, Australia Monash Univ, Monash Immunol & Stem Cell Labs, STRIP, Clayton, Vic 3800, Australia

Layton, Daniel
论文数: 0 引用数: 0
h-index: 0
机构:
Monash Univ, Monash Immunol & Stem Cell Labs, STRIP, Clayton, Vic 3800, Australia Monash Univ, Monash Immunol & Stem Cell Labs, STRIP, Clayton, Vic 3800, Australia

论文数: 引用数:
h-index:
机构:

Boyd, Richard L.
论文数: 0 引用数: 0
h-index: 0
机构:
Monash Univ, Monash Immunol & Stem Cell Labs, STRIP, Clayton, Vic 3800, Australia Monash Univ, Monash Immunol & Stem Cell Labs, STRIP, Clayton, Vic 3800, Australia
[5]
Medical progress: Hematopoietic stem-cell transplantation
[J].
Copelan, EA
.
NEW ENGLAND JOURNAL OF MEDICINE,
2006, 354 (17)
:1813-1826

Copelan, EA
论文数: 0 引用数: 0
h-index: 0
机构: Ohio State Univ, Arthur G James Canc Hosp, Columbus, OH 43210 USA
[6]
Immunogenicity of Pluripotent Stem Cells and Their Derivatives
[J].
de Almeida, Patricia E.
;
Ransohoff, Julia D.
;
Nahid, Abu
;
Wu, Joseph C.
.
CIRCULATION RESEARCH,
2013, 112 (03)
:549-561

de Almeida, Patricia E.
论文数: 0 引用数: 0
h-index: 0
机构:
Stanford Univ, Sch Med, Dept Med, Div Cardiol, Stanford, CA 94305 USA
Stanford Univ, Sch Med, Inst Immun Transplantat & Infect, Stanford, CA 94305 USA Stanford Univ, Sch Med, Dept Med, Div Cardiol, Stanford, CA 94305 USA

Ransohoff, Julia D.
论文数: 0 引用数: 0
h-index: 0
机构:
Stanford Univ, Sch Med, Dept Med, Div Cardiol, Stanford, CA 94305 USA Stanford Univ, Sch Med, Dept Med, Div Cardiol, Stanford, CA 94305 USA

Nahid, Abu
论文数: 0 引用数: 0
h-index: 0
机构:
Stanford Univ, Sch Med, Dept Med, Div Cardiol, Stanford, CA 94305 USA Stanford Univ, Sch Med, Dept Med, Div Cardiol, Stanford, CA 94305 USA

Wu, Joseph C.
论文数: 0 引用数: 0
h-index: 0
机构:
Stanford Univ, Sch Med, Dept Med, Div Cardiol, Stanford, CA 94305 USA
Stanford Univ, Sch Med, Inst Immun Transplantat & Infect, Stanford, CA 94305 USA
Stanford Univ, Sch Med, Stanford Cardiovasc Inst, Stanford, CA 94305 USA Stanford Univ, Sch Med, Dept Med, Div Cardiol, Stanford, CA 94305 USA
[7]
How to cross immunogenetic hurdles to human embryonic stem cell transplantation
[J].
de Rham, Casimir
;
Villard, Jean
.
SEMINARS IN IMMUNOPATHOLOGY,
2011, 33 (06)
:525-534

de Rham, Casimir
论文数: 0 引用数: 0
h-index: 0
机构:
Geneva Univ Hosp & Med Sch, Transplant Immunol Unit, Div Immunol & Allergy, CH-1211 Geneva 14, Switzerland
Geneva Univ Hosp & Med Sch, Div Lab Med, CH-1211 Geneva 14, Switzerland Geneva Univ Hosp & Med Sch, Transplant Immunol Unit, Div Immunol & Allergy, CH-1211 Geneva 14, Switzerland

论文数: 引用数:
h-index:
机构:
[8]
Human embryonic stem cells and their differentiated derivatives are less susceptible to immune rejection than adult cells
[J].
Drukker, Micha
;
Katchman, Helena
;
Katz, Gil
;
Friedman, Smadar Even-Tov
;
Shezen, Elias
;
Hornstein, Eran
;
Mandelboim, Ofer
;
Reisner, Yair
;
Benvenisty, Nissim
.
STEM CELLS,
2006, 24 (02)
:221-229

Drukker, Micha
论文数: 0 引用数: 0
h-index: 0
机构:
Hebrew Univ Jerusalem, Silberman Inst Life Sci, Dept Genet, IL-91904 Jerusalem, Israel Hebrew Univ Jerusalem, Silberman Inst Life Sci, Dept Genet, IL-91904 Jerusalem, Israel

Katchman, Helena
论文数: 0 引用数: 0
h-index: 0
机构: Hebrew Univ Jerusalem, Silberman Inst Life Sci, Dept Genet, IL-91904 Jerusalem, Israel

Katz, Gil
论文数: 0 引用数: 0
h-index: 0
机构: Hebrew Univ Jerusalem, Silberman Inst Life Sci, Dept Genet, IL-91904 Jerusalem, Israel

Friedman, Smadar Even-Tov
论文数: 0 引用数: 0
h-index: 0
机构: Hebrew Univ Jerusalem, Silberman Inst Life Sci, Dept Genet, IL-91904 Jerusalem, Israel

Shezen, Elias
论文数: 0 引用数: 0
h-index: 0
机构: Hebrew Univ Jerusalem, Silberman Inst Life Sci, Dept Genet, IL-91904 Jerusalem, Israel

Hornstein, Eran
论文数: 0 引用数: 0
h-index: 0
机构: Hebrew Univ Jerusalem, Silberman Inst Life Sci, Dept Genet, IL-91904 Jerusalem, Israel

Mandelboim, Ofer
论文数: 0 引用数: 0
h-index: 0
机构: Hebrew Univ Jerusalem, Silberman Inst Life Sci, Dept Genet, IL-91904 Jerusalem, Israel

论文数: 引用数:
h-index:
机构:

Benvenisty, Nissim
论文数: 0 引用数: 0
h-index: 0
机构: Hebrew Univ Jerusalem, Silberman Inst Life Sci, Dept Genet, IL-91904 Jerusalem, Israel
[9]
The challenge of immunogenicity in the quest for induced pluripotency
[J].
Fairchild, Paul J.
.
NATURE REVIEWS IMMUNOLOGY,
2010, 10 (12)
:868-875

Fairchild, Paul J.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Oxford, Sir William Dunn Sch Pathol, Oxford OX1 3RE, England Univ Oxford, Sir William Dunn Sch Pathol, Oxford OX1 3RE, England
[10]
Establishment of a Brazilian Line of Human Embryonic Stem Cells in Defined Medium: Implications for Cell Therapy in an Ethnically Diverse Population
[J].
Fraga, Ana M.
;
Sukoyan, Marina
;
Rajan, Prithi
;
de Almeida Ferreira Braga, Daniela Paes
;
Iaconelli, Assumpto, Jr.
;
Franco, Jose Goncalves, Jr.
;
Borges, Edson, Jr.
;
Pereira, Lygia V.
.
CELL TRANSPLANTATION,
2011, 20 (03)
:431-440

Fraga, Ana M.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Sao Paulo, Lab Genet Mol, Inst Biociencias, BR-05508090 Sao Paulo, Brazil
Univ Sao Paulo, Lab Nacl Celulas Tronco Embrionarias LaNCE, Inst Biociencias, BR-05508090 Sao Paulo, Brazil
Inst Nacl Ciencia & Tecnol Celulas Tronco & Terap, Ribeirao Preto, Brazil Univ Sao Paulo, Lab Genet Mol, Inst Biociencias, BR-05508090 Sao Paulo, Brazil

Sukoyan, Marina
论文数: 0 引用数: 0
h-index: 0
机构:
Russian Acad Sci, Novosibirsk, Russia Univ Sao Paulo, Lab Genet Mol, Inst Biociencias, BR-05508090 Sao Paulo, Brazil

Rajan, Prithi
论文数: 0 引用数: 0
h-index: 0
机构:
Agni Consulting Serv, San Marcos, CA USA Univ Sao Paulo, Lab Genet Mol, Inst Biociencias, BR-05508090 Sao Paulo, Brazil

de Almeida Ferreira Braga, Daniela Paes
论文数: 0 引用数: 0
h-index: 0
机构:
Fertil & Assoc Inst Sapientiae, Sao Paulo, Brazil Univ Sao Paulo, Lab Genet Mol, Inst Biociencias, BR-05508090 Sao Paulo, Brazil

Iaconelli, Assumpto, Jr.
论文数: 0 引用数: 0
h-index: 0
机构:
Fertil & Assoc Inst Sapientiae, Sao Paulo, Brazil Univ Sao Paulo, Lab Genet Mol, Inst Biociencias, BR-05508090 Sao Paulo, Brazil

Franco, Jose Goncalves, Jr.
论文数: 0 引用数: 0
h-index: 0
机构:
Ctr Reprod Humana Prof Franco Junior, Ribeirao Preto, Brazil Univ Sao Paulo, Lab Genet Mol, Inst Biociencias, BR-05508090 Sao Paulo, Brazil

Borges, Edson, Jr.
论文数: 0 引用数: 0
h-index: 0
机构:
Fertil & Assoc Inst Sapientiae, Sao Paulo, Brazil Univ Sao Paulo, Lab Genet Mol, Inst Biociencias, BR-05508090 Sao Paulo, Brazil

Pereira, Lygia V.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Sao Paulo, Lab Genet Mol, Inst Biociencias, BR-05508090 Sao Paulo, Brazil
Univ Sao Paulo, Lab Nacl Celulas Tronco Embrionarias LaNCE, Inst Biociencias, BR-05508090 Sao Paulo, Brazil
Inst Nacl Ciencia & Tecnol Celulas Tronco & Terap, Ribeirao Preto, Brazil Univ Sao Paulo, Lab Genet Mol, Inst Biociencias, BR-05508090 Sao Paulo, Brazil