Jak Inhibitors Reverse Vitiligo in Mice but Do Not Deplete Skin Resident Memory T Cells

被引:31
作者
Azzolino, Vincent [1 ]
Zapata, Lucio, Jr. [1 ]
Garg, Madhuri [1 ]
Gjoni, Melina [1 ]
Riding, Rebecca L. [1 ]
Strassner, James P. [1 ]
Richmond, Jillian M. [1 ]
Harris, John E. [1 ]
机构
[1] Univ Massachusetts, Sch Med, Dept Dermatol, Worcester, MA 01605 USA
关键词
MOUSE MODEL; REPIGMENTATION; TOFACITINIB; DEPIGMENTATION; PATHOGENESIS;
D O I
10.1016/j.jid.2020.04.027
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
[No abstract available]
引用
收藏
页码:182 / +
页数:4
相关论文
共 19 条
[1]   Simvastatin Prevents and Reverses Depigmentation in a Mouse Model of Vitiligo [J].
Agarwal, Priti ;
Rashighi, Mehdi ;
Essien, Kingsley I. ;
Richmond, Jillian M. ;
Randall, Louise ;
Pazoki-Toroudi, Hamidreza ;
Hunter, Christopher A. ;
Harris, John E. .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2015, 135 (04) :1080-1088
[2]   Vitiligo Skin Is Imprinted with Resident Memory CD8 T Cells Expressing CXCR3 [J].
Boniface, Katia ;
Jacquemin, Clement ;
Darrigade, Anne-Sophie ;
Dessarthe, Benoit ;
Martins, Christina ;
Boukhedouni, Nesrine ;
Vernisse, Charlotte ;
Grasseau, Alexis ;
Thiolat, Denis ;
Rambert, Jerome ;
Lucchese, Fabienne ;
Bertolotti, Antoine ;
Ezzedine, Khaled ;
Taieb, Alain ;
Seneschal, Julien .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2018, 138 (02) :355-364
[3]   Maintenance Therapy of Adult Vitiligo with 0.1% Tacrolimus Ointment: A Randomized, Double Blind, Placebo-Controlled Study [J].
Cavalie, Marine ;
Ezzedine, Khaled ;
Fontas, Eric ;
Montaudie, Henri ;
Castela, Emeline ;
Bahadoran, Philippe ;
Taieb, Alain ;
Lacour, Jean-Philippe ;
Passeron, Thierry .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2015, 135 (04) :970-974
[4]   CD49a Expression Defines Tissue-Resident CD8+ T Cells Poised for Cytotoxic Function in Human Skin [J].
Cheuk, Stanley ;
Schlums, Heinrich ;
Serezal, Irene Gallais ;
Martini, Elisa ;
Chiang, Samuel C. ;
Marquardt, Nicole ;
Gibbs, Anna ;
Detlofsson, Ebba ;
Introini, Andrea ;
Forkel, Marianne ;
Hoog, Charlotte ;
Tjernlund, Annelie ;
Michaelsson, Jakob ;
Folkersen, Lasse ;
Mjosberg, Jenny ;
Blomqvist, Lennart ;
Ehrstrom, Marcus ;
Stahle, Mona ;
Bryceson, Yenan T. ;
Eidsmo, Liv .
IMMUNITY, 2017, 46 (02) :287-300
[5]   Tofacitinib Citrate for the Treatment of Vitiligo A Pathogenesis-Directed Therapy [J].
Craiglow, Brittany G. ;
King, Brett A. .
JAMA DERMATOLOGY, 2015, 151 (10) :1110-1112
[6]   JAK inhibitors in dermatology: The promise of a new drug class [J].
Damsky, William ;
King, Brett A. .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2017, 76 (04) :736-744
[7]   Vitiligo: Mechanisms of Pathogenesis and Treatment [J].
Frisoli, Michael L. ;
Essien, Kingsley ;
Harris, John E. .
ANNUAL REVIEW OF IMMUNOLOGY, VOL 38, 2020, 38 :621-648
[8]   Rapid skin repigmentation on oral ruxolitinib in a patient with coexistent vitiligo and alopecia areata (AA) [J].
Harris, John E. ;
Rashighi, Mehdi ;
Nhan Nguyen ;
Jabbari, Ali ;
Ulerio, Grace ;
Clynes, Raphael ;
Christiano, Angela M. ;
Mackay-Wiggan, Julian .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2016, 74 (02) :370-371
[9]   A Mouse Model of Vitiligo with Focused Epidermal Depigmentation Requires IFN-γ for Autoreactive CD8+ T-Cell Accumulation in the Skin [J].
Harris, John E. ;
Harris, Tajie H. ;
Weninger, Wolfgang ;
Wherry, E. John ;
Hunter, Christopher A. ;
Turka, Laurence A. .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2012, 132 (07) :1869-1876
[10]   Rapid Repigmentation of Vitiligo Using Tofacitinib Plus Low-Dose. Narrowband UV-B Phototherapy [J].
Kim, Sa Rang ;
Heaton, Henry ;
Liu, Lucy Y. ;
King, Brett A. .
JAMA DERMATOLOGY, 2018, 154 (03) :370-371