Direct modeling of foveal pit morphology from distortion-corrected OCT images

被引:8
作者
Breher, Katharina [1 ]
Agarwala, Rajat [1 ]
Leube, Alexander [1 ,2 ]
Wahl, Siegfried [1 ,2 ]
机构
[1] Eberhard Karls Univ Tuebingen, Inst Ophthalm Res, Elfriede Aulhorn Str 7, D-72076 Tubingen, Germany
[2] Carl Zeiss Vis Int GmbH, Turnstr 27, D-73430 Aalen, Germany
关键词
OPTICAL COHERENCE TOMOGRAPHY; SHAPE; THICKNESS;
D O I
10.1364/BOE.10.004815
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Inherent distortions affect the spatial geometry of optical coherence tomography (OCT) images and consequently the foveal pit dimensions. Distortion correction provides an accurate anatomical representation of the retinal shape. A novel approach that automatically extracts foveal pit metrics from distortion-corrected OCT images using a sum of Gaussian function is presented. Foveal width, depth and slope were determined in 292 eyes with low fitting errors and high repeatability. Comparisons to undistorted scans revealed significant differences. To conclude, the internal OCT distortions affect the measurements of the foveal pit with their correction providing further insights into the role of foveal morphology in retinal pathologies and refractive development. (C) 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
引用
收藏
页码:4815 / 4824
页数:10
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