Long-Term Survival of the Very Elderly Undergoing Aortic Valve Surgery

被引:76
作者
Likosky, Donald S. [1 ,2 ,3 ]
Sorensen, Meredith J. [1 ,2 ,3 ]
Dacey, Lawrence J. [1 ,2 ,3 ]
Baribeau, Yvon R. [4 ]
Leavitt, Bruce J. [5 ]
DiScipio, Anthony W. [1 ,2 ,3 ]
Hernandez, Felix, Jr. [6 ]
Cochran, Richard P. [7 ]
Quinn, Reed [8 ]
Helm, Robert E. [9 ]
Charlesworth, David C. [4 ]
Clough, Robert A. [6 ]
Malenka, David J. [1 ,2 ,3 ]
Sisto, Donato A. [9 ]
Sardella, Gerald [10 ]
Olmstead, Elaine M. [1 ,2 ,3 ]
Ross, Cathy S. [1 ,2 ,3 ]
O'Connor, Gerald T. [1 ,2 ,3 ]
机构
[1] Dartmouth Hitchcock Med Ctr, Dept Med, Hanover, NH USA
[2] Dartmouth Hitchcock Med Ctr, Dept Surg, Hanover, NH USA
[3] Dartmouth Hitchcock Med Ctr, Dept Community & Family Med, Hanover, NH USA
[4] Catholic Med Ctr, Dept Surg, Manchester, NH USA
[5] Fletcher Allen Hlth Care, Dept Surg, Burlington, VT USA
[6] Eastern Maine Med Ctr, Dept Surg, Bangor, ME USA
[7] Cent Maine Med Ctr, Dept Surg, Lewiston, ME USA
[8] Maine Med Ctr, Dept Surg, Portland, ME 04102 USA
[9] Portsmouth Reg Hosp, Dept Surg, Portsmouth, NH USA
[10] Concord Hosp, Dept Surg, Concord, NH USA
关键词
valves; coronary disease; survival; aging; BYPASS GRAFT-SURGERY; QUALITY-OF-LIFE; HOSPITAL MORTALITY; CARDIAC-SURGERY; AGED; 80; REPLACEMENT; OCTOGENARIANS; STENOSIS; OUTCOMES; RISK;
D O I
10.1161/CIRCULATIONAHA.108.842641
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background-Increasing numbers of the very elderly are undergoing aortic valve procedures. We describe the short- and long-term survivorship for this cohort. Methods and Results-We conducted a cohort study of 7584 consecutive patients undergoing open aortic valve surgery without (51.1%; AVR) or with (48.9%; AVR + CABG) concomitant coronary artery bypass graft surgery between November 10, 1987 through June 30, 2006. Patient records were linked to the Social Security Administration's Death Master File. Survivorship was stratified by age and concomitant CABG surgery. During 39 835 person-years of follow-up, there were 2877 deaths. Among AVR, there were 3304 patients <80 years of age, 419 patients 80 to 84 years, and 156 patients >= 85 years (24 patients >90 years). Among AVR+CABG patients, there were 2890 patients <80 years of age, 577 patients 80 to 84 years, and 238 patients >= 85 years (22 patients >90 years). Median survivorship for patients undergoing isolated AVR was 11.5 years (<80 years), 6.8 years (80 to 84 years), 6.2 years (>= 85 years); for patients undergoing AVR+CABG, median survivorship was 9.4 years (<80 years), 6.8 years (80 to 84 years), and 7.1 years (>= 85 years). Among both procedures, adjusted survivorship was significantly different across strata of age (P<0.001). These findings are similar to life expectancy of the general population from actuarial tables: 80 to 84 years (7 years) and >= 85 years (5 years). Conclusions-Survivorship among octogenarians is favorable, with more than half the patients surviving more than 6 years after their surgery. Concomitant CABG surgery does not diminish median survivorship among patients >80 years of age. (Circulation. 2009; 120[suppl 1]: S127-S133.)
引用
收藏
页码:S127 / S133
页数:7
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