Hyaluronic acid-polypyrrole nanoparticles as pH-responsive theranostics

被引:63
作者
Park, Dongjin [1 ]
Cho, Youngnam [2 ]
Goh, Sung-Ho [3 ]
Choi, Yongdoo [1 ]
机构
[1] Natl Canc Ctr, Mol Imaging & Therapy Branch, Goyang Si 410769, Gyeonggi Do, South Korea
[2] Natl Canc Ctr, New Expt Therapeut Branch, Goyang Si 410769, Gyeonggi Do, South Korea
[3] Natl Canc Ctr, Canc Genom Branch, Goyang Si 410769, Gyeonggi Do, South Korea
关键词
PHOTODYNAMIC THERAPY; MOTEXAFIN LUTETIUM; PROLIFERATION;
D O I
10.1039/c4cc06349j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Doxorubicin-loaded hyaluronic acid-polypyrrole nanoparticles were developed for pH-responsive activatable fluorescence imaging and therapy of proliferating macrophages.
引用
收藏
页码:15014 / 15017
页数:4
相关论文
共 19 条
[1]   Macrophage proliferation and apoptosis in atherosclerosis [J].
Andres, Vicente ;
Pello, Oscar M. ;
Silvestre-Roig, Carlos .
CURRENT OPINION IN LIPIDOLOGY, 2012, 23 (05) :429-438
[2]   Polypyrrole nanoparticles for high-performance in vivo near-infrared photothermal cancer therapy [J].
Chen, Mei ;
Fang, Xiaoliang ;
Tang, Shaoheng ;
Zheng, Nanfeng .
CHEMICAL COMMUNICATIONS, 2012, 48 (71) :8934-8936
[3]   Hyaluronic Acid Immobilized Magnetic Nanoparticles for Active Targeting and Imaging of Macrophages [J].
Kamat, Medha ;
El-Boubbou, Kheireddine ;
Zhu, David C. ;
Lansdell, Teri ;
Lu, Xiaowei ;
Li, Wei ;
Huang, Xuefei .
BIOCONJUGATE CHEMISTRY, 2010, 21 (11) :2128-2135
[4]   Phase I drug and light dose-escalation trial of motexafin lutetium and far red light activation (phototherapy) in subjects with coronary artery disease undergoing percutaneous coronary intervention and stent deployment - Procedural and long-term results [J].
Kereiakes, DJ ;
Szyniszewski, AM ;
Wahr, D ;
Herrmann, HC ;
Simon, DI ;
Rogers, C ;
Kramer, P ;
Shear, W ;
Yeung, AC ;
Shunk, KA ;
Chou, TM ;
Popma, J ;
Fitzgerald, P ;
Carroll, TE ;
Forer, D ;
Adelman, DC .
CIRCULATION, 2003, 108 (11) :1310-1315
[5]   ROS-Responsive Activatable Photosensitizing Agent for Imaging and Photodynamic Therapy of Activated Macrophages [J].
Kim, Hyunjin ;
Kim, Youngmi ;
Kim, In-Hoo ;
Kim, Kyungtae ;
Choi, Yongdoo .
THERANOSTICS, 2014, 4 (01) :1-11
[6]   Macrophage-targeted photodynamic therapy: Scavenger receptor expression and activation state [J].
Liu, Q ;
Hamblin, MR .
INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY, 2005, 18 (03) :391-402
[7]   Perspectives and opportunities for nanomedicine in the management of atherosclerosis [J].
Lobatto, Mark E. ;
Fuster, Valentin ;
Fayad, Zahi A. ;
Mulder, Willem J. M. .
NATURE REVIEWS DRUG DISCOVERY, 2011, 10 (11) :835-852
[8]   Atherosclerosis [J].
Lusis, AJ .
NATURE, 2000, 407 (6801) :233-241
[9]   A macrophage-targeted theranostic nanoparticle for biomedical applications [J].
McCarthy, Jason R. ;
Jaffer, Farouc A. ;
Weissleder, Ralph .
SMALL, 2006, 2 (8-9) :983-987
[10]   A Light-Activated Theranostic Nanoagent for Targeted Macrophage Ablation in Inflammatory Atherosclerosis [J].
McCarthy, Jason R. ;
Korngold, Ethan ;
Weissleder, Ralph ;
Jaffer, Farouc A. .
SMALL, 2010, 6 (18) :2041-2049