Sclerosing polidocanol injections in chronic painful tennis elbow-promising results in a pilot study

被引:53
作者
Zeisig, Eva [1 ]
Ohberg, Lars
Alfredson, Hakan
机构
[1] Umea Univ, Dept Surg & Perioperat Sci, Sports Med Unit, S-90187 Umea, Sweden
[2] Umea Univ, Dept Radiat Sci, S-90187 Umea, Sweden
[3] Umea Univ, Natl Inst Working Life, Dept Musculoskeletal Res, S-90187 Umea, Sweden
基金
瑞典研究理事会;
关键词
tennis elbow; pain; vascularity; treatment; sclerosing injections;
D O I
10.1007/s00167-006-0156-0
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Sclerosing polidocanol injections targeting the area with neovessels (vascularity) have been demonstrated to give promising clinical results in patients with chronic painful Achilles and patellar tendinosis. Recently, we demonstrated vascularity in the extensor origin in patients with chronic painful tennis elbow, but not in controls with pain-free elbows. In this pilot study, 11 patients (four men and seven women, mean age 46 years) with the diagnosis of tennis elbow in altogether 13 elbows, were included. All patients had a long duration of pain symptoms (mean 23 months), and ultrasonography (US) + colour Doppler (CD) examination showed structural tendon changes with hypo-echoic areas, and a vascularity, corresponding to the painful area in the extensor origin. All patients were treated with US- and CD-guided injections of the sclerosing substance polidocanol, targeting the area with vascularity. At 8-month follow-up after treatment, there was a good clinical result in 11/13 elbows. Extensor origin pain during wrist loading activities (recorded on a VAS-scale) was significantly reduced (mean VAS from 75 to 34; P < 0.003), and maximal grip strength was significantly increased (from 29 to 40 kg; P < 0.025). Our findings indicate that one treatment with sclerosing polidocanol injections, targeting the area with vascularity in the extensor origin, has a potential to reduce the tendon pain and increase grip strength, in patients with chronic painful tennis elbow.
引用
收藏
页码:1218 / 1224
页数:7
相关论文
共 25 条
[1]   In vivo investigation of ECRB tendons with microdialysis technique - no signs of inflammation but high amounts of glutamate in tennis elbow [J].
Alfredson, H ;
Ljung, BO ;
Thorsen, K ;
Lorentzon, R .
ACTA ORTHOPAEDICA SCANDINAVICA, 2000, 71 (05) :475-479
[2]   Neovascularisation in chronic painful patellar tendinosis -: promising results after sclerosing neovessels outside the tendon challenge the need for surgery [J].
Alfredson, H ;
Öhberg, L .
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY, 2005, 13 (02) :74-80
[3]   Sclerosing injections to areas of neo-vascularisation reduce pain in chronic Achilles tendinopathy:: a double-blind randomised controlled trial [J].
Alfredson, H ;
Öhberg, L .
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY, 2005, 13 (04) :338-344
[4]   Is vasculo-neural ingrowth the cause of pain in chronic Achilles tendinosis?: An investigation using ultrasonography and colour Doppler, immunohistochemistry, and diagnostic injections [J].
Alfredson, H ;
Öhberg, L ;
Forsgren, S .
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY, 2003, 11 (05) :334-338
[5]  
[Anonymous], 2002, COCHRANE DB SYST REV
[6]  
Assendelft WJJ, 1996, BRIT J GEN PRACT, V46, P209
[7]   A systematic review and meta-analysis of clinical trials on physical interventions for lateral epicondylalgia [J].
Bisset, L ;
Paungmali, A ;
Vicenzino, B ;
Beller, E .
BRITISH JOURNAL OF SPORTS MEDICINE, 2005, 39 (07) :411-422
[8]   The innervation pattern of the human Achilles tendon: studies of the normal and tendinosis tendon with markers for general and sensory innervation [J].
Bjur, D ;
Alfredson, H ;
Forsgren, S .
CELL AND TISSUE RESEARCH, 2005, 320 (01) :201-206
[9]  
BUCHBINDER R, 2002, COCHRANE DB SYST REV, DOI DOI 10.1002/14651858.CD003525
[10]   Vascularity and pain in the patellar tendon of adult jumping athletes: a 5 month longitudinal study [J].
Cook, JL ;
Malliaras, P ;
De Luca, J ;
Ptasznik, R ;
Morris, M .
BRITISH JOURNAL OF SPORTS MEDICINE, 2005, 39 (07) :458-461