Molecular imprinting of protein by coordinate interaction

被引:7
|
作者
Wang, Jun [1 ]
Hua, Zhen Dong [1 ]
Chen, Zhi Yong [1 ]
Li, Yuan Zong [1 ]
Zhao, Mei Ping [1 ]
机构
[1] Peking Univ, Coll Chem & Mol Engn, Key Lab Bioorgan Chem & Mol Engn, Beijing 100871, Peoples R China
基金
中国国家自然科学基金;
关键词
Molecular imprinted hydrogel; Bovine serum albumin; Copper ion; RECOGNITION; POLYMER;
D O I
10.1016/j.cclet.2008.12.035
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In this article, a novel strong interaction by forming complex between bovine serum albumin (BSA) and copper ion was utilized for the preparation of molecular imprinted hydrogel in aqueous solution. Results show that the inclusion of copper ion in preparation can bridge the template BSA and functional monomers together and improve the imprinting effect compared to the polymer made without copper ion added. High selectivity factor and large adsorption capacity are also observed for the obtained BSA-imprinted hydrogel. (C) 2008 Mei Ping Zhao. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All fights reserved.
引用
收藏
页码:747 / 750
页数:4
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