Potential for Improved Glycemic Control with Dietary Momordica charantia in Patients with Insulin Resistance and Pre-Diabetes

被引：43

作者：

Efird, Jimmy T. ^{[1
,2
]}

Choi, Yuk Ming ^{[3
]}

Davies, Stephen W. ^{[4
]}

Mehra, Sanjay ^{[5
]}

Anderson, Ethan J. ^{[6
,7
]}

Katunga, Lalage A. ^{[6
]}

机构：

[1] E Carolina Univ, East Carolina Heart Inst, Greenville, NC 27834 USA

[2] E Carolina Univ, Ctr Hlth Dispar, Brody Sch Med, Greenville, NC 27834 USA

[3] Univ N Carolina, Sch Nursing, Adult Gerontol Nurse Practitioner Program, Greensboro, NC 27402 USA

[4] Univ Virginia, Sch Med, Dept Gen Surg, Charlottesville, VA 22908 USA

[5] E Carolina Univ, Brody Sch Med, Dept Cardiovasc Sci, Greenville, NC 27834 USA

[6] E Carolina Univ, Dept Pharmacol & Toxicol, Brody Sch Med, Greenville, NC 27834 USA

[7] E Carolina Univ, East Carolina Diabet & Obes Inst ECDOI, East Carolina Heart Inst, Greenville, NC 27834 USA

来源：

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH | 2014年 / 11卷 / 02期

关键词：

Momordica charantia; bitter melon; insulin resistance; pre-diabetes; glycemic control; TYPE-2; DIABETES-MELLITUS; BITTER-MELON; HYPOGLYCEMIC ACTIVITY; AMERICAN ASSOCIATION; GLUCOSE-TOLERANCE; CLINICAL-TRIALS; PLANT SOURCE; BETA-CELLS; EXTRACT; RATS;

D O I：

10.3390/ijerph110202328

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Bitter Melon (Momordica charantia) is a widely used traditional remedy for hyperglycemia. While the medicinal properties of this plant have been studied extensively using in vitro and animal models, the clinical efficacy and safety in humans is largely unknown. This review discusses the benefits and limitations of bitter melon supplementation in the context of epidemic levels of insulin resistance and pre-diabetes throughout the world.

引用

页码：2328 / 2345

页数：18

共 66 条

[1] Effect of metformin treatment on multiple cardiovascular disease risk factors in patients with type 2 diabetes mellitus [J].

Abbasi, F ;

Chu, JW ;

McLaughlin, T ;

Lamendola, C ;

Leary, ET ;

Reaven, GM .

METABOLISM-CLINICAL AND EXPERIMENTAL, 2004, 53 (02) :159-164

[2]

Abel Willie M, 2013, Front Public Health, V1, P66, DOI 10.3389/fpubh.2013.00066

[3] ABORTIFACIENT EFFECTS OF THE ROOTS OF MOMORDICA-ANGUSTISEPALA [J].

AGUWA, CN ;

MITTAL, GC .

JOURNAL OF ETHNOPHARMACOLOGY, 1983, 7 (02) :169-173

[4]

Ahmad N, 1999, Bangladesh Med Res Counc Bull, V25, P11

[5]

Akhtar M S, 1982, J Pak Med Assoc, V32, P106

[6]

[Anonymous], COMPL ALT INT HLTH W

[7]

[Anonymous], PHILIPPINE J INTERNA

[8]

[Anonymous], 2011, National diabetes fact sheet: National estimates and general information on diabetes and prediabetes in the United States

[9] INTERACTION BETWEEN CURRY INGREDIENT (KARELA) AND DRUG (CHLORPROPAMIDE) [J].

ASLAM, M ;

STOCKLEY, IH .

LANCET, 1979, 1 (8116) :607-607

[10] CLINICAL-TRIAL IN PATIENTS WITH DIABETES-MELLITUS OF AN INSULIN-LIKE COMPOUND OBTAINED FROM PLANT SOURCE [J].

BALDWA, VS ;

BHANDARI, CM ;

PANGARIA, A ;

GOYAL, RK .

UPSALA JOURNAL OF MEDICAL SCIENCES, 1977, 82 (01) :39-41

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