Conducting Polymers for Neural Prosthetic and Neural Interface Applications

被引：296

作者：

Green, Rylie ^{[1
]}

Abidian, Mohammad Reza ^{[2
,3
]}

机构：

[1] Univ New S Wales, Grad Sch Biomed Engn, Sydney, NSW 2052, Australia

[2] Penn State Univ, Mat Res Inst, Dept Chem Engn, Dept Mat Sci & Engn,Biomed Engn Dept, University Pk, PA 16802 USA

[3] Penn State Univ, Huck Inst Life Sci, University Pk, PA 16802 USA

来源：

ADVANCED MATERIALS | 2015年 / 27卷 / 46期

基金：

美国国家卫生研究院;

关键词：

SILICON MICROELECTRODE ARRAYS; CONTROLLED DRUG-DELIVERY; BRAIN-TISSUE RESPONSE; IN-VITRO; POLY(3,4-ETHYLENEDIOXYTHIOPHENE) PEDOT; NEURITE OUTGROWTH; ELECTROCHEMICAL POLYMERIZATION; ELECTRICAL-STIMULATION; ELECTROACTIVE POLYMER; MECHANICAL-PROPERTIES;

D O I：

10.1002/adma.201501810

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Neural-interfacing devices are an artificial mechanism for restoring or supplementing the function of the nervous system, lost as a result of injury or disease. Conducting polymers (CPs) are gaining significant attention due to their capacity to meet the performance criteria of a number of neuronal therapies including recording and stimulating neural activity, the regeneration of neural tissue and the delivery of bioactive molecules for mediating device-tissue interactions. CPs form a flexible platform technology that enables the development of tailored materials for a range of neuronal diagnostic and treatment therapies. In this review, the application of CPs for neural prostheses and other neural interfacing devices is discussed, with a specific focus on neural recording, neural stimulation, neural regeneration, and therapeutic drug delivery.

引用

页码：7620 / 7637

页数：18

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