Daily Variation of UV-induced Erythema and the Action of Solar Filters

被引:0
|
作者
Flo, Ana [1 ]
Calpena, Ana C. [1 ]
Diez-Noguera, Antoni [2 ]
del Pozo, Alfons [1 ]
Cambras, Trinitat [2 ]
机构
[1] Univ Barcelona, Dept Farm & Tecnol Farmaceut, Fac Farm & Ciencies Alimentacio, Barcelona, Spain
[2] Univ Barcelona, Dept Fisiol & Bioquim, Fac Farm & Ciencies Alimentacio, Barcelona, Spain
关键词
SKIN FUNCTION; RADIATION; COLOR;
D O I
10.1111/php.12670
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
UV rays may cause several degrees of skin damage, which makes sunscreen research necessary. In addition, skin sensitivity shows daily variations, which can interfere in the detection of the efficacy of the filters. Here, we studied the UV-induced erythema in hairless rats at two times of the day (light and darkness) using a colorimeter method. The effect of an emulsion with solar filters with or without melatonin was also assayed. Results indicate that the value of a* (from CIELAB color space values L* a* b) was the most useful variable to evaluate the erythema. However, at the UV intensity used, erythema was only detected when irradiation was carried out during the activity phase of the animal, enabling the detection of the protective action of the sunscreen at this time. Thus, daily variations in skin sensitivity have been demonstrated and should be taken into account in dermatological research.
引用
收藏
页码:632 / 635
页数:4
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