The effect of obesity on patients with mild chronic obstructive pulmonary disease: results from KNHANES 2010 to 2012

被引:9
作者
Park, Ju-Hee [1 ]
Lee, Jung-Kyu [1 ]
Heo, Eun Young [1 ]
Kim, Deog Kyeom [1 ]
Chung, Hee Soon [1 ]
机构
[1] Seoul Natl Univ, Div Pulm & Crit Care Med, Seoul Metropolitan Govt, Med Ctr, Seoul, South Korea
来源
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE | 2017年 / 12卷
关键词
COPD; obesity; comorbidity; KNHANES; spirometry; lung function; AIRWAY-OBSTRUCTION; METABOLIC SYNDROME; HEALTH; COMORBIDITIES; COPD; PREVALENCE; TIOTROPIUM; TRIAL; RISK;
D O I
10.2147/COPD.S126192
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Purpose: A low body mass index has been associated with high mortalities in patients with chronic obstructive pulmonary disease (COPD), and studies reveal that obesity aggravates the clinical effects of COPD. We investigated the impact of obesity on patients newly identified with COPD. Patients and methods: This population-based, cross-sectional study, used data from the Korea National Health and Nutrition Examination Survey (KNHANES) conducted from 2010 to 2012. Through analyses of data from this survey, we compared concurrent comorbid diseases, symptoms, and lung functions between an obese and nonobese group of patients with COPD. Results: In total, 618 participants were diagnosed with COPD and the average forced expired volume in 1 s (FEV1) was 79.47%+/- 0.69%. Of the total, 30.5% of the subjects were categorized into an obese group. Subjects in the obese group were likely to have metabolic syndrome (P, 0.001), hypertension (P=0.02), and a higher number of comorbidities compared to the nonobese group (2.3 +/- 0.1 vs 2.0 +/- 0.1, P=0.02). In addition, subjects in the obese group showed a lower forced vital capacity (FVC) than subjects in the nonobese group, even after adjusting for covariates (average FVC%, 89.32 +/- 1.26 vs 92.52%+/- 0.72%, P=0.037). There were no significant differences in the adjusted FEV1% and adjusted FEV1/FVC between the groups. Conclusions: Among subjects newly identified with mild COPD, participants in the obese group had more comorbid conditions and showed a lower FVC compared with subjects in the nonobese group, even after adjustment of covariates. These findings show that a combination of obesity and COPD may be a severe phenotype; therefore, early attention should be paid to obesity for the management of COPD patients.
引用
收藏
页码:757 / 763
页数:7
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