Citric Acid/MCM-48 Catalyzed Multicomponent Reaction: An Efficient Method for the Novel Synthesis of Quinoline Derivatives

A facile, efficient and suitable green approach has been designated for the one-pot synthesis of quinoline derivatives in the presence of citric acid doped MCM-48 (CAMCM-48) as a heterogeneous catalyst. The prepared material was characterized by using various techniques like P-XRD, SEM, TEM, TGA, FTIR and structural properties was determined by BET analysis. The reaction progressed efficiently under ethanol solvent system at room temperature condition to afford the corresponding products. This protocol offers many advantages such as simple synthesis, easy work-up, short reaction times (15 min), good stability, reusability and no chromatographic separation techniques plus excellent yields (91-98%).