Citric Acid/MCM-48 Catalyzed Multicomponent Reaction: An Efficient Method for the Novel Synthesis of Quinoline Derivatives

被引：12

作者：

Akpotu, Samson O. ^{[1
,2
]}

Moodley, Brenda ^{[1
]}

Vamsi, Boddu ^{[3
]}

Ofomaja, Augustine ^{[2
]}

Maddila, Suresh ^{[1
,3
]}

Jonnalagadda, Sreekantha B. ^{[1
]}

机构：

[1] Univ KwaZulu Natal, Sch Chem & Phys, Westville Campus,Chilten Hills,Private Bag 54001, ZA-4000 Durban, South Africa

[2] Vaal Univ Techol, Dept Chem, PBag X021, ZA-1900 Vanderbijlpak, South Africa

[3] GITAM Univ, GITAM Inst Sci, Dept Chem, Visakhapatnam, Andhra Pradesh, India

来源：

CHEMISTRYSELECT | 2019年 / 4卷 / 23期

基金：

新加坡国家研究基金会;

关键词：

Green synthesis; Heterogeneous catalyst; MCM-48; One-pot reaction; Quinolines; ONE-POT SYNTHESIS; MOLECULAR DOCKING; REUSABLE CATALYST; ANTICANCER; FACILE; DISCOVERY; GREEN;

D O I：

10.1002/slct.201900907

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A facile, efficient and suitable green approach has been designated for the one-pot synthesis of quinoline derivatives in the presence of citric acid doped MCM-48 (CAMCM-48) as a heterogeneous catalyst. The prepared material was characterized by using various techniques like P-XRD, SEM, TEM, TGA, FTIR and structural properties was determined by BET analysis. The reaction progressed efficiently under ethanol solvent system at room temperature condition to afford the corresponding products. This protocol offers many advantages such as simple synthesis, easy work-up, short reaction times (15 min), good stability, reusability and no chromatographic separation techniques plus excellent yields (91-98%).

引用

页码：7003 / 7009

页数：7

共 44 条

[1] Ultrasound promotes one-pot synthesis of 1,4-dihydropyridine and imidazo[1,2-a]quinoline derivatives, catalyzed by ZnO nanoparticles
Abaszadeh, Mehdi
Seifi, Mohammad
Asadipour, Ali
[J]. RESEARCH ON CHEMICAL INTERMEDIATES, 2015, 41 (08) : 5229 - 5238
[2] Molecular docking, discovery, synthesis, and pharmacological properties of new 6-substituted-2-(3-phenoxyphenyl)-4-phenyl quinoline derivatives; an approach to developing potent DNA gyrase inhibitors/antibacterial agents
Alagumuthu, Manikandan
Arumugam, Sivakumar
[J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 25 (04) : 1448 - 1455
[3] Alexandria P. T., 2016, ORG BIOMOL CHEM, V14, P6611
[4] Evaluation of magnetically recyclable nano-Fe3O4 as a green catalyst for the synthesis of mono- and bis-tetrahydro-4H-chromene and mono and bis 1,4-dihydropyridine derivatives
Amirheidari, Bagher
Seifi, Mohammad
Abaszadeh, Mehdi
[J]. RESEARCH ON CHEMICAL INTERMEDIATES, 2016, 42 (04) : 3413 - 3423
[5] Nano-zirconia as an excellent nano support for immobilization of sulfonic acid: a new, efficient and highly recyclable heterogeneous solid acid nanocatalyst for multicomponent reactions
Amoozadeh, Ali
Rahmani, Salman
Bitaraf, Mehrnoosh
Abadi, Fatemeh Bolghan
Tabrizian, Elham
[J]. NEW JOURNAL OF CHEMISTRY, 2016, 40 (01) : 770 - 780
[6] Avelino C., 2008, CHEM SOC REV, V37, P2096
[7] V2O5/ZrO2 as an efficient reusable catalyst for the facile, green, one-pot synthesis of novel functionalized 1,4-dihydropyridine derivatives
Bhaskaruni, Sandeep V. H. S.
Maddila, Suresh
van Zyl, Werner E.
Jonnalagadda, Sreekantha B.
[J]. CATALYSIS TODAY, 2018, 309 : 276 - 281
[8] Tetrahydropyranodiquinolin-8-amines as new, non hepatotoxic, antioxidant, and acetylcholinesterase inhibitors for Alzheimer's disease therapy
Dgachi, Youssef
Sokolov, Olga
Luzet, Vincent
Godyn, Justyna
Panek, Dawid
Bonet, Alexandre
Martin, Helene
Iriepa, Isabel
Moraleda, Ignacio
Garcia-Iriepa, Cristina
Janockova, Jana
Richert, Lysiane
Soukup, Ondrej
Malawska, Barbara
Chabchoub, Fakher
Marco-Contelles, Jose
Ismaili, Lhassane
[J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 126 : 576 - 589
[9] Estelle C. C., 2012, ACS IND ENG CHEM RES, V51, P2864
[10] Strategies for Innovation in Multicomponent Reaction Design
Ganem, Bruce
[J]. ACCOUNTS OF CHEMICAL RESEARCH, 2009, 42 (03) : 463 - 472

← 1 2 3 4 5 →