Chemical Profile and Biological Activities of Essential Oil from Artemisia vulgaris L. Cultivated in Brazil

被引:38
|
作者
Malik, Sonia [1 ,2 ]
Silva de Mesquita, Ludmilla Santos [3 ]
Silva, Carolina Rocha [4 ]
Carvalho de Mesquita, Jose Wilson [3 ]
Rocha, Emmeline de Sa [3 ]
Bose, Jayakumar [2 ]
Abiri, Rambod [5 ,6 ]
Silva Figueiredo, Patricia de Maria [3 ]
Costa-Junior, Livio M. [4 ]
机构
[1] Univ Fed Maranhao, Biol & Hlth Sci Ctr, Grad Program Hlth Sci, BR-65085580 Sao Luis, MA, Brazil
[2] Univ Adelaide, Waite Res Inst, Sch Agr Food & Wine, Australian Res Council Ctr Excellence Plant Energ, PMB 1, Glen Osmond, SA 5064, Australia
[3] Univ Fed Maranhao, Biol & Hlth Sci Ctr, Dept Pharm, BR-65085580 Sao Luis, MA, Brazil
[4] Univ Fed Maranhao, Biol & Hlth Sci Ctr, Dept Pathol, BR-65085580 Sao Luis, MA, Brazil
[5] Univ Putra Malaysia, Fac Biotechnol & Biomol Sci, Dept Biochem, Upm Serdang 43400, Selangor De, Malaysia
[6] Islamic Azad Univ, Young Researchers & Elite Club, Kermanshah, Iran
关键词
anthelmintic; antimicrobial; (compositae); caryophyllene; germacrene-D; humulene; GCMS-chromatography; MEDICINAL-PLANTS; BETA-CARYOPHYLLENE; ALPHA-HUMULENE; SCHISTOSOMICIDAL ACTIVITY; ANTHELMINTIC ACTIVITY; HAEMONCHUS-CONTORTUS; GERMACRENE D; EXTRACTS; SESQUITERPENE; INHIBITION;
D O I
10.3390/ph12020049
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Essential oil from the leaves of Artemisia vulgaris L. (Compositae) cultivated in Brazil was investigated for its chemical composition and biological activities including antibacterial, antifungal, and anthelmintic. The constituents of essential oils isolated by hydro-distillation were examined by GC-MS and a total of 18 components were identified. The essential oil was dominated by oxygenated sesquiterpenes (44.4%), sesquiterpene hydrocarbons (33.3%), and oxygenated monoterpenes (16.6%). Caryophyllene (37.45%), germacrene D (16.17%), and humulene (13.66%) were the major components. The essential oils from A. vulgaris showed bactericidal and fungicidal properties against Staphylococcus aureus and Candida albicans, respectively. Anthelmintic activity against Haemonchus contortus was absent in this essential oil. Altogether above results indicate that essential oils from A. vulgaris can be used for various medicinal purposes.
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页数:10
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