Molecular mechanisms in bile formation

被引:0
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作者
Meier, PJ [1 ]
Stieger, B [1 ]
机构
[1] Univ Zurich Hosp, Dept Med 1, Div Clin Pharmacol & Toxicol, CH-8091 Zurich, Switzerland
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中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Active canalicular secretion of bile salts and non-bile salt organic anions represents the major driving force of hepatic bile formation. The most important carriers involved have now been cloned on both the basolateral and canalicular sides of hepatocytes. Elucidation of their structure, transport properties, and regulation is an important step forward in the ultimate understanding of the molecular physiology of bile formation.
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页码:89 / 93
页数:5
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